N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine

Base Information

• Chemical Name: N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine
• CAS No.: 1070773-71-5
• Molecular Formula: C₂₀H₂₃NO
• Molecular Weight: 293.409
• Mol file: 1070773-71-5.mol

Synonyms:N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine

Chemical Property of N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine

There total 2 articles about N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

4-methoxy-benzaldehyde (123-11-5) + N-butylamine (109-73-9,85404-21-3) + phenylacetylene (536-74-3) → N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine (1070773-71-5)

Guidance literature:

With copper(l) iodide; at 75 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.201800109

Reference yield: 30.0%

4-methoxy-benzaldehyde (123-11-5) + N-butylamine (109-73-9,85404-21-3) + 1-Phenyl-2-(trimethylsilyl)acetylene (2170-06-1) → N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine (1070773-71-5)

Guidance literature:

With copper(II) bis(trifluoromethanesulfonate); copper(l) chloride; In acetonitrile; at 100 ℃; for 24h;

DOI:10.1055/S-2008-1077790

Reference yield: 79.0%

N-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl) butan-1-amine (1070773-71-5) + carbon dioxide (124-38-9,18923-20-1) → 5-benzyl-3-butyl-4-(4-methoxyphenyl)-3H-oxazol-2-one

Guidance literature:

With 1-butyl-3-methylimidazolium trifluoromethanesulfonimide; 3-butyl-1-methylimidazolium acetate; at 100 ℃; for 30h; under 750.075 Torr; Green chemistry;

DOI:10.1039/c4gc02033b

upstream raw materials:

4-methoxy-benzaldehyde

N-butylamine

1-Phenyl-2-(trimethylsilyl)acetylene

phenylacetylene