2-isopropyl-1H-imidazole-4,5-dicarboxylic acid

Base Information

• Chemical Name: 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid
• CAS No.: 51294-23-6
• Molecular Formula: C₈H₁₀N₂O₄
• Molecular Weight: 198.178
• Mol file: 51294-23-6.mol

Synonyms:2-isopropyl-1H-imidazole-4,5-dicarboxylic acid

Chemical Property of 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid

Chemical Property:

• Melting Point: 231 °C (decomp)
• Boiling Point: 530.2±35.0 °C(Predicted)
• Density: 1.456±0.06 g/cm3(Predicted)

Purity/Quality:

2-(1-methylethyl)-1H-Imidazole-4,5-dicarboxylicacid 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid

There total 4 articles about 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

2-isopropylbenzimidazole (5851-43-4) → 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid (51294-23-6)

Guidance literature:

With sulfuric acid; dihydrogen peroxide; In water; at 100 - 120 ℃; for 0.5h;

DOI:10.1134/S1070363218050055

Reference yield: 27.0%

2,3-dinitroxybutanedioic acid + isobutyraldehyde (78-84-2) → 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid (51294-23-6)

Guidance literature:

2,3-dinitroxybutanedioic acid; With ammonium hydroxide; cooling;

isobutyraldehyde; In water; at -4 - 0 ℃; for 20h; Further stages.;

DOI:10.1134/S1070363207050234

Reference yield:

Lg-tartaric acid-dinitrate (13171-63-6) + isobutyraldehyde (78-84-2) → 2-isopropyl-1H-imidazole-4,5-dicarboxylic acid (51294-23-6)

Guidance literature:

With ammonia;

upstream raw materials:

L_g-tartaric acid-dinitrate

isobutyraldehyde

2-isopropylbenzimidazole

Downstream raw materials:

2-isopropylimidazole

methylammonium carbonate

2-Isopropyl-1-(2',3',5'-tri-O-benzoyl-β-D-ribofuranosyl)imidazol-4,5-dicarbonsaeure-dimethylester