C₂₈H₃₅N₇O

Base Information

• Chemical Name: C₂₈H₃₅N₇O
• CAS No.: 1014703-42-4
• Molecular Formula: C₂₈H₃₅N₇O
• Molecular Weight: 485.632
• Mol file: 1014703-42-4.mol

Synonyms:C₂₈H₃₅N₇O

Chemical Property of C₂₈H₃₅N₇O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₈H₃₅N₇O

There total 10 articles about C₂₈H₃₅N₇O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C33H43N7O3 (1014703-06-0) → C28H35N7O (1014703-42-4)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 2h;

Reference yield:

1-(t-butoxycarbonyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine (192940-81-1,209667-56-1) → C28H35N7O (1014703-42-4)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hypochlorite; sodium hydrogencarbonate / 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / dichloromethane; water / 4 h / 0 - 20 °C

2.1: dichloromethane / 0.5 h / 0 °C

2.2: 0 - 20 °C

3.1: hydrogen / palladium(II) hydroxide/carbon / ethanol / 48 h / 20 °C / 760.05 Torr

4.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 °C

5.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h / 20 °C

With hydrogenchloride; sodium hypochlorite; hydrogen; sodium hydrogencarbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium(II) hydroxide/carbon; In 1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

3,5-Dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester (35691-93-1) → C28H35N7O (1014703-42-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium carbonate; N,N`-dimethylethylenediamine / copper(l) iodide / 1,4-dioxane / 16 h / 110 °C

2.1: potassium hydroxide / ethanol; water / 24 h / 40 °C

2.2: pH 4

3.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane; N,N-dimethyl-formamide / 20 °C

4.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 2 h / 20 °C

With hydrogenchloride; potassium hydroxide; potassium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; N,N`-dimethylethylenediamine; copper(l) iodide; In 1,4-dioxane; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

C₃₃H₄₃N₇O₃

3,5-Dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester

1-(t-butoxycarbonyl)-3-phenyl-3-(2-hydroxyethyl)pyrrolidine

2-(3-phenyl-5-yl-pyrrolidin-3-yl)-ethanol

Downstream raw materials:

(5-{2-[1-(3,3-difluoro-cyclobutanecarbonyl)-3-phenyl-pyrrolidin-3-yl]-ethyl}-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-(3,5-dimethyl-1-pyrimidin-5-yl-1H-pyrazol-4-yl)-methanone

Refernces