4-Allyloxy-piperidine-1-carboxylic acid tert-butyl ester

Base Information

• Chemical Name: 4-Allyloxy-piperidine-1-carboxylic acid tert-butyl ester
• CAS No.: 163210-43-3
• Molecular Formula: C₁₃H₂₃NO₃
• Molecular Weight: 241.331
• Mol file: 163210-43-3.mol

Synonyms:1-Piperidinecarboxylicacid, 4-(2-propenyloxy)-, 1,1-dimethylethyl ester (9CI); tert-Butyl4-(allyloxy)piperidine-1-carboxylate

Chemical Property of 4-Allyloxy-piperidine-1-carboxylic acid tert-butyl ester

Chemical Property:

• PSA: 38.77000
• LogP: 2.52640

Purity/Quality:

99% ^*data from raw suppliers

4-ALLYLOXY-PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Allyloxy-piperidine-1-carboxylic acid tert-butyl ester

There total 3 articles about 4-Allyloxy-piperidine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

allyl bromide (106-95-6) + t-butyl 4-hydroxy piperidine-1-carboxylate (109384-19-2) → tert-butyl 4-(allyloxy)piperidine-1-carboxylate (163210-43-3)

Guidance literature:

t-butyl 4-hydroxy piperidine-1-carboxylate; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃;

allyl bromide; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 17h;

Reference yield:

allyl bromide (106-95-6) → tert-butyl 4-(allyloxy)piperidine-1-carboxylate (163210-43-3)

Guidance literature:

t-butyl 4-hydroxy piperidine-1-carboxylate; With sodium hydride; In tetrahydrofuran; for 0.166667h;

allyl bromide; In tetrahydrofuran; for 72h;

Reference yield:

→ tert-butyl 4-(allyloxy)piperidine-1-carboxylate (163210-43-3)

Guidance literature:

upstream raw materials:

allyl bromide

t-butyl 4-hydroxy piperidine-1-carboxylate

Downstream raw materials:

tert-butyl 4-(3-hydroxypropoxy)piperidine-1-carboxylate

tert-butyl 4-(2-hydroxyethoxy)piperidine-1-carboxylate