Technology Process of 4-hexyl-2-methoxy-1-(2-methoxyphenoxy)benzene
There total 7 articles about 4-hexyl-2-methoxy-1-(2-methoxyphenoxy)benzene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-(hexyl-2-methoxyphenoxy)-3-methoxyaniline;
With
sulfuric acid; sodium nitrite;
In
ethanol; water;
at 0 ℃;
for 0.5h;
With
zinc;
In
ethanol; water;
at 20 ℃;
for 3h;
Reflux;
DOI:10.1002/cmdc.201300429
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: pentyltriphenylphosphonium bromide / cyclohexane; tetrahydrofuran / 0.5 h / -78 °C
1.2: 2 h / Cooling
2.1: palladium on activated charcoal; hydrogen / ethanol / 6 h / 760.05 Torr
3.1: 18-crown-6 ether; potassium carbonate / N,N-dimethyl-formamide / 3 h / 20 - 110 °C
4.1: hydrogenchloride / water; ethanol / 0.08 h / 0 - 20 °C
5.1: sodium nitrite; sulfuric acid / water; ethanol / 0.5 h / 0 °C
5.2: 3 h / 20 °C / Reflux
With
hydrogenchloride; 18-crown-6 ether; sulfuric acid; palladium on activated charcoal; pentyltriphenylphosphonium bromide; hydrogen; potassium carbonate; sodium nitrite;
In
tetrahydrofuran; ethanol; cyclohexane; water; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201300429
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: palladium on activated charcoal; hydrogen / ethanol / 6 h / 760.05 Torr
2.1: 18-crown-6 ether; potassium carbonate / N,N-dimethyl-formamide / 3 h / 20 - 110 °C
3.1: hydrogenchloride / water; ethanol / 0.08 h / 0 - 20 °C
4.1: sodium nitrite; sulfuric acid / water; ethanol / 0.5 h / 0 °C
4.2: 3 h / 20 °C / Reflux
With
hydrogenchloride; 18-crown-6 ether; sulfuric acid; palladium on activated charcoal; hydrogen; potassium carbonate; sodium nitrite;
In
ethanol; water; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201300429
