diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate

Base Information

Chemical Name:diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate
CAS No.:1050534-49-0
Molecular Formula:C₂₃H₃₁F₂N₂O₆P
Molecular Weight:500.48
Hs Code.:

Synonyms:diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate

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Chemical Property of diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate

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Technology Process of diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate

There total 1 articles about diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 1050534-41-2
diisopropyl 1,1-difluoro-5-(p-toluenesulfonyloxy)pentylphosphonate

: 4330-20-5
N-3-benzoylthymine

: 1050534-49-0
diisopropyl 5-(3-benzoyl-5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-1,1-difluoropentylphosphonate

Guidance literature:: With N,N,N',N'-tetramethylguanidine; In dimethyl sulfoxide; at 20 ℃; for 15h; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol801443s