(+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate

Base Information Edit

Chemical Name:(+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate
CAS No.:732277-73-5
Molecular Formula:C₁₉H₁₈N₄O₄S
Molecular Weight:398.442
Hs Code.:
Mol file:732277-73-5.mol

Synonyms:(+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate

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Chemical Property of (+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate Edit

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Technology Process of (+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate

There total 2 articles about (+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 732276-72-1
(+/-)-8-Methyl-5-(4-nitrophenyl)-7-thiocarbamoyl-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine

: 74-88-4
methyl iodide

: 732277-73-5
(+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate

Guidance literature:: With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20 ℃;

Reference yield:

: 143692-49-3,161832-62-8,161832-63-9
1-(4-Nitrophenyl)-4-methyl-7,8-methylenedioxy-3,4-dihydro-5H-2,3-benzodiazepine

: 732277-73-5
(+/-)-8-methyl-5-(4-nitrophenyl)-8,9-dihydro-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-7-S-methyl-thiocarboximidate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 6 h / 100 - 110 °C

2: potassium carbonate / DMF (N,N-dimethyl-formamide) / 20 °C

With potassium carbonate; acetic acid; In DMF (N,N-dimethyl-formamide);