3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole

Base Information

Chemical Name:3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole
CAS No.:144657-65-8
Molecular Formula:C₁₅H₂₁N₃O₂
Molecular Weight:275.351
Hs Code.:29339900
Mol file:144657-65-8.mol

3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole

Synonyms:1-Boc-3-[(dimethylamino)methyl]-7-azaindole;3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole

Suppliers and Price of 3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1-Boc-3-[(dimethylamino)methyl]-7-azaindole 97%
1g
$ 107.00

Crysdot
tert-Butyl3-((dimethylamino)methyl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate 97%
5g
$ 303.00

American Custom Chemicals Corporation
1-BOC-3-[(DIMETHYLAMINO)METHYL]-7-AZAINDOLE 95.00%
1G
$ 719.89

Total 8 raw suppliers

Chemical Property of 3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole

Chemical Property:

Melting Point:97-101 °C
PSA：47.36000
LogP:2.88110

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Boc-3-[(dimethylamino)methyl]-7-azaindole 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25-36/37/38
Safety Statements: 26-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole

There total 2 articles about 3-Dimethylaminomethyl-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester, 1-tert-Butoxycarbonyl-3-[(dimethylamino)methyl]-7-azaindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.7%

: 5654-92-2
7-azagramine

: 24424-99-5
di-tert-butyl dicarbonate

: 144657-65-8
1-tert-butyloxycarbonyl-3-(N-dimethylaminomethyl)-7-azaindole

Guidance literature:: 7-azagramine; With sodium hydride; In tetrahydrofuran; for 0.166667h;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 271-63-6
7-Azaindole

: 144657-65-8
1-tert-butyloxycarbonyl-3-(N-dimethylaminomethyl)-7-azaindole

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / glacial acetic acid / H₂O / 16 h / 60 °C

2: 1.) NaH / 1.) HMPA, 0.5 h, 2.) HMPA, 21 deg C, 2 h

With sodium hydride; acetic acid; In water;