(4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Base Information

Chemical Name:(4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde
CAS No.:130718-76-2
Molecular Formula:C₁₃H₁₆O₄
Molecular Weight:236.268
Hs Code.:

Synonyms:(4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Suppliers and Price of (4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of (4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

There total 16 articles about (4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 130718-85-3
cis-4--2,2-dimethyl-5-(4-methoxyphenyl)-1,3-dioxolan

: 130718-76-2,130796-30-4,130796-31-5
cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Guidance literature:: With boron trifluoride diethyl etherate; mercury(II) oxide; In tetrahydrofuran; water; for 1h; Ambient temperature;

Reference yield: 73.0%

: 130718-74-0
(4R,5R)-cis-4--5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan

: 130718-76-2
(4R,5R)-cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Guidance literature:: With boron trifluoride diethyl etherate; mercury(II) oxide; In tetrahydrofuran; water; for 1h; Ambient temperature;

Reference yield:

: 13305-14-1
methyl 2-hydroxy-2-(4-methoxyphenyl)acetate

: 130718-76-2,130796-30-4,130796-31-5
cis-5-(4-methoxyphenyl)-2,2-dimethyl-1,3-dioxolan-4-carbaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: 100 percent / imidazole, 4-(dimethylamino)pyridine / diethyl ether / Ambient temperature

2: 1.) LDA / 1.) hexane, THF, -78 deg C, 30 min, 2.) -78 deg C, 30 min

3: 95 percent / 1 M hydrochloric acid / 18 h / Ambient temperature

4: 100 percent / NaBH₄ / ethanol / 0.67 h / Ambient temperature

5: 88 percent / 4-toluenesulfonic acid / Ambient temperature

6: 94 percent / yellow mercuric oxide, BF₃*Et₂O / tetrahydrofuran; H₂O / 1 h / Ambient temperature

With 1H-imidazole; hydrogenchloride; dmap; sodium tetrahydroborate; boron trifluoride diethyl etherate; toluene-4-sulfonic acid; mercury(II) oxide; lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; ethanol; water;