1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate

Base Information

Chemical Name:1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate
CAS No.:1200399-46-7
Molecular Formula:C₁₆H₁₉ClN₂O₂S
Molecular Weight:338.858
Hs Code.:

Synonyms:1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate

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Chemical Property of 1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate

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Technology Process of 1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate

There total 2 articles about 1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 938001-17-3
2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazole-5-carboxylic acid

: 75-65-0
tert-butyl alcohol

: 1200399-46-7
1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate

Guidance literature:: With diphenyl phosphoryl azide; triethylamine; for 3h; Reflux; Inert atmosphere;

Reference yield:

: 17518-48-8
4-chlorophenylthioacetamide

: 1200399-46-7
1,1-dimethylethyl {2-[(4-chlorophenyl)methyl]-4-methyl-1,3-thiazol-5-yl}carbamate

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol / 4 h / Reflux

2: water; sodium hydroxide / ethanol / 1 h / Reflux

3: diphenyl phosphoryl azide; triethylamine / 3 h / Reflux; Inert atmosphere

With diphenyl phosphoryl azide; water; triethylamine; sodium hydroxide; In ethanol;