tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate

Base Information Edit

Chemical Name:tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
CAS No.:143557-91-9
Molecular Formula:C12H21 N O3
Molecular Weight:227.304
Hs Code.:2933990090
European Community (EC) Number:808-934-8,847-692-8
DSSTox Substance ID:DTXSID90457281
Wikidata:Q76416735
Mol file:143557-91-9.mol

Synonyms:194222-05-4;tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;143557-91-9;N-Boc-Nortropine;tert-Butyl 3-exo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;(1R,3s,5S)-tert-Butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;Tert-butyl (1R,5S)-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;tert-butyl (1R,3s,5S)-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane;tert-Butyl 3-exo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;8-azabicyclo[3.2.1]octane-8-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester, (3-exo)-;tert-butyl (1R,3r,5S)-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;exo-N-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane;tert-butyl-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;MFCD16294321;MFCD22409620;SCHEMBL219188;SCHEMBL641026;SCHEMBL1023170;3-exo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester;DTXSID90457281;MFCD09966165;AKOS016008920;AKOS025402026;AC-3288;CS-W019359;DS-6339;AS-53526;CS-0048100;3-exo-8-Boc-8-azabicyclo[3.2.1]octan-3-ol;P16621;EN300-6488756;EN300-6489446;A880211;Z1505702606;tert-butyl exo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;tert-Butyl3-exo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;tert-butyl3-exo-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate;8-Azabicyclo[3.2.1]octane-8-carboxylic acid, 3-hydroxy-,1,1-dimethylethyl ester;tert-Butyl (1R,5S)-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate, AldrichCPR

Suppliers and Price of tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane
1 g
$ 24.00

SynQuest Laboratories
endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane
5 g
$ 64.00

SynQuest Laboratories
endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane
25 g
$ 232.00

Matrix Scientific
endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane
1g
$ 95.00

Matrix Scientific
endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane
5g
$ 261.00

Crysdot
tert-Butyl3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
10g
$ 69.00

Crysdot
tert-Butyl3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
25g
$ 134.00

Crysdot
tert-Butyl3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
100g
$ 436.00

Crysdot
tert-Butyl3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate 97%
5g
$ 45.00

Chemenu
endo-8-boc-3-hydroxy-8-azabicyclo[3.2.1]octane 97%
50g
$ 202.00

Total 37 raw suppliers

Chemical Property of tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate Edit

Chemical Property:

Vapor Pressure:1.48E-05mmHg at 25°C
Melting Point:141.5℃
Refractive Index:1.52
Boiling Point:328℃
PKA:14.79±0.20(Predicted)
Flash Point:152℃
PSA：49.77000
Density:1.146
LogP:1.84710
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:227.15214353
Heavy Atom Count:16
Complexity:271

Purity/Quality:

97% ^*data from raw suppliers

endo-8-Boc-3-hydroxy-8-azabicyclo[3.2.1]octane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 22-36/37/38
Safety Statements: 22-26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1C2CCC1CC(C2)O
Isomeric SMILES:CC(C)(C)OC(=O)N1[C@@H]2CC[C@H]1CC(C2)O

Technology Process of tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate

There total 27 articles about tert-Butyl 3-endo-3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%