Technology Process of (3E,5E,7E)-8-(p-isopropylphenyl)-1-trimethylsilylocta-3,5,7-trien-1-yne
There total 4 articles about (3E,5E,7E)-8-(p-isopropylphenyl)-1-trimethylsilylocta-3,5,7-trien-1-yne which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide;
for 4h;
Ambient temperature;
DOI:10.1016/S0040-4020(99)00123-4
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 93 percent / Red-Al / diethyl ether; toluene / 5 h / -20 - 36 °C
2: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
3: 93 percent / PdCl2(PPh3)2, CuI, piperidine / 4 h / Ambient temperature
With
piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; methanesulfonyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
diethyl ether; toluene;
DOI:10.1016/S0040-4020(99)00123-4
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 83 percent / PdCl2(PPh3)2, CuI, piperidine / diethyl ether / 4 h / 15 - 20 °C
2: 93 percent / Red-Al / diethyl ether; toluene / 5 h / -20 - 36 °C
3: 1.) methanesulfonyl chloride, triethylamine, 2.) DBU / 1.) CH2Cl2, room temperature, 30 min, 2.) CH2Cl2, room temperature
4: 93 percent / PdCl2(PPh3)2, CuI, piperidine / 4 h / Ambient temperature
With
piperidine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; methanesulfonyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; sodium bis(2-methoxyethoxy)aluminium dihydride;
In
diethyl ether; toluene;
DOI:10.1016/S0040-4020(99)00123-4
