2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine

Base Information

• Chemical Name: 2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine
• CAS No.: 1425935-13-2
• Molecular Formula: C₂₅H₂₄Cl₃N₃O₂S
• Molecular Weight: 536.909
• Mol file: 1425935-13-2.mol

Synonyms:2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine

Chemical Property of 2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine

There total 2 articles about 2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

4-toluenesulfonyl azide (941-55-9) + 2,2,2-Trichloro-N-(4-methyl-benzyl)-acetamidine (60523-79-7) + phenylacetylene (536-74-3) → 2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine (1425935-13-2)

Guidance literature:

With copper(l) iodide; triethylamine; In acetonitrile; at 20 ℃; for 8h; Inert atmosphere;

DOI:10.1055/s-0032-1317952

Reference yield:

para-methylbenzylamine (104-84-7) → 2,2,2-trichloro-N′-(4-methylbenzyl)-N-[1-(4-methylphenylsulfonylamino)-2-phenylethylidene]acetamidine (1425935-13-2)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / 0.5 h / 20 °C

2: copper(l) iodide; triethylamine / acetonitrile / 8 h / 20 °C / Inert atmosphere

With copper(l) iodide; triethylamine; In acetonitrile;

DOI:10.1055/s-0032-1317952

upstream raw materials:

4-toluenesulfonyl azide

2,2,2-Trichloro-N-(4-methyl-benzyl)-acetamidine

phenylacetylene

para-methylbenzylamine