PROPYL-ALPHA-PHENYLPROPIONATE

Base Information

• Chemical Name: PROPYL-ALPHA-PHENYLPROPIONATE
• CAS No.: 157239-52-6
• Molecular Formula: C₁₂H₁₆O₂
• Molecular Weight: 192.258
• Mol file: 157239-52-6.mol

Synonyms:Benzeneaceticacid, a-methyl-, propyl ester, (R)-;(R)-2-Phenylpropionic acid 1-propanol ester

Chemical Property of PROPYL-ALPHA-PHENYLPROPIONATE

Chemical Property:

• PSA: 26.30000
• LogP: 2.74330

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PROPYL-ALPHA-PHENYLPROPIONATE

There total 20 articles about PROPYL-ALPHA-PHENYLPROPIONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.3%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + propan-1-ol (71-23-8) + carbon monoxide (201230-82-2) → propyl 2-phenylpropanoate (91668-61-0,157239-52-6)

Guidance literature:

With 0.17percent Pd-P-OP/LSI-600 catalyst; In toluene; at 80 ℃; for 3.5h; under 22502.3 Torr; Autoclave;

DOI:10.1039/c3cy00842h

Reference yield: 83.0%

propan-1-ol (71-23-8) + (4R,2'R)-3-(2'-phenylpropionyl)-4-phenyl-oxazolidin-2-one (198344-48-8) → propyl ester of (R)-2-phenylpropanoic acid (157239-52-6)

Guidance literature:

With ytterbium(III) triflate; at 80 ℃; for 20h;

DOI:10.1021/acs.joc.8b02451

Reference yield: 38.0%

propan-1-ol (71-23-8) + C14H18O4 (176438-83-8) → 2-methylpropyl propyl carbonate ester (40882-93-7) + propyl ester of (R)-2-phenylpropanoic acid (157239-52-6)

Guidance literature:

With Lipozyme LM; In various solvent(s); for 20h; Ambient temperature;

DOI:10.1016/0040-4020(96)00083-X

upstream raw materials:

styrene

propan-1-ol

carbon monoxide

propyl methanoate