Technology Process of C27H29BrN6O3
There total 5 articles about C27H29BrN6O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
isopropyl alcohol;
at 100 ℃;
for 16h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: boron tribromide / dichloromethane / 20 °C / Cooling with ice bath
1.2: -78 - 20 °C
2.1: sodium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / tetrahydrofuran; water / 1.5 h / 80 °C
3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0.33 h / 20 °C
3.2: 15 h
4.1: hydrogen / palladium 10% on activated carbon / methanol / 17 h / 20 °C / 760.05 Torr / Inert atmosphere of argon
5.1: isopropyl alcohol / 16 h / 100 °C
With
hydrogen; boron tribromide; sodium carbonate; triphenylphosphine; diethylazodicarboxylate;
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; dichloromethane; water; isopropyl alcohol;
2.1: Suzuki Coupling / 3.1: Mitsunobu reaction / 3.2: Mitsunobu reaction;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 0.33 h / 20 °C
1.2: 15 h
2.1: hydrogen / palladium 10% on activated carbon / methanol / 17 h / 20 °C / 760.05 Torr / Inert atmosphere of argon
3.1: isopropyl alcohol / 16 h / 100 °C
With
hydrogen; triphenylphosphine; diethylazodicarboxylate;
palladium 10% on activated carbon;
In
tetrahydrofuran; methanol; isopropyl alcohol;
1.1: Mitsunobu reaction / 1.2: Mitsunobu reaction;