2,4,6-trichlorobenzoic pivalic anhydride

Base Information

• Chemical Name: 2,4,6-trichlorobenzoic pivalic anhydride
• CAS No.: 343220-59-7
• Molecular Formula: C₁₂H₁₁Cl₃O₃
• Molecular Weight: 309.577
• Mol file: 343220-59-7.mol

Synonyms:2,4,6-trichlorobenzoic pivalic anhydride

Chemical Property of 2,4,6-trichlorobenzoic pivalic anhydride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4,6-trichlorobenzoic pivalic anhydride

There total 3 articles about 2,4,6-trichlorobenzoic pivalic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pivalaldehyde (630-19-3) → 2,2-dimethylpropanoic anhydride (1538-75-6) + 2,4,6-trichlorobenzoic pivalic anhydride (343220-59-7)

Guidance literature:

Multi-step reaction with 2 steps

1: trichloroisocyanuric acid / dichloromethane / 20 °C / Inert atmosphere

2: triethylamine / 0 °C / Inert atmosphere

With trichloroisocyanuric acid; triethylamine; In dichloromethane;

DOI:10.1039/C6NJ02625G

Reference yield:

2,4,6-trichlorobenzoic acid (50-43-1) + pivaloyl chloride (3282-30-2) → 2,2-dimethylpropanoic anhydride (1538-75-6) + 2,4,6-trichlorobenzoic pivalic anhydride (343220-59-7)

Guidance literature:

With triethylamine; at 0 ℃; Inert atmosphere;

DOI:10.1039/C6NJ02625G

Reference yield:

2,4,6-trichlorobenzoyl chloride (4136-95-2) + Trimethylacetic acid (75-98-9) → 2,4,6-trichlorobenzoic pivalic anhydride (343220-59-7)

Guidance literature:

With triethylamine; In dichloromethane; for 1h;

DOI:10.1246/bcsj.54.943

upstream raw materials:

2,4,6-trichlorobenzoyl chloride

Trimethylacetic acid

2,4,6-trichlorobenzoic acid

pivaloyl chloride

Downstream raw materials:

S-phenyl 2,2-dimethylpropanethioate

Refernces

• 1、 Kawanami, Yasuhiro,Dainobu, Yuichiro,Inanaga, Junji,Katsuki, Tsutomu,Yamaguchi, Masaru. "Synthesis of Thiol Esters by Carboxylic Trichlorobenzoic Anhydrides". . p. 943 - 944. Retrieved 2007/10/02.