(S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Base Information

Chemical Name:(S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol
CAS No.:1448530-84-4
Molecular Formula:C₁₇H₃₀BrNO₃Si
Molecular Weight:404.42
Hs Code.:

Synonyms:(S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Suppliers and Price of (S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

There total 4 articles about (S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1448530-83-3
(S)-1-(2-bromo-5-((tert-butyldimethylsilyl)oxy)-4-methoxy-3-methylphenyl)-3-((tert-butyldimethylsilyl)oxy)propan-2-amine

: 1448530-84-4
(S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 0.416667h; Inert atmosphere;
DOI:10.1016/j.tet.2013.05.009

Reference yield:

: 1177255-31-0
bromotyrosinol

: 1448530-84-4
(S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: ammonium chloride / water; dichloromethane / 2 h / 20 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.42 h / 0 °C / Inert atmosphere

With dmap; tetrabutyl ammonium fluoride; ammonium chloride; triethylamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/j.tet.2013.05.009

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 1448530-84-4
(S)-5-(2-amino-3-((tert-butyldimethylsilyl)oxy)propyl)-4-bromo-2-methoxy-3-methylphenol

Guidance literature:: Multi-step reaction with 3 steps

1: dmap; triethylamine / dichloromethane / 3 h / 20 °C / Inert atmosphere

2: ammonium chloride / water; dichloromethane / 2 h / 20 °C / Inert atmosphere

3: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.42 h / 0 °C / Inert atmosphere

With dmap; tetrabutyl ammonium fluoride; ammonium chloride; triethylamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1016/j.tet.2013.05.009