Acetamide, N-(4-cyanophenyl)-N-ethyl-

Base Information

• Chemical Name: Acetamide, N-(4-cyanophenyl)-N-ethyl-
• CAS No.: 155053-12-6
• Molecular Formula: C11H12 N2 O
• Molecular Weight: 188.23
• Mol file: 155053-12-6.mol

Synonyms:Acetamide, N-(4-cyanophenyl)-N-ethyl-

Chemical Property of Acetamide, N-(4-cyanophenyl)-N-ethyl-

Chemical Property:

• PSA: 44.10000
• LogP: 1.93108

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetamide, N-(4-cyanophenyl)-N-ethyl-

There total 1 articles about Acetamide, N-(4-cyanophenyl)-N-ethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl iodide (75-03-6) + N-(4-cyanophenyl)acetamide (35704-19-9) → N-(4-cyanophenyl)-N-ethylacetamide (155053-12-6)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Inert atmosphere;

Reference yield:

N-(4-cyanophenyl)-N-ethylacetamide (155053-12-6) → 4-(ethylamino)benzonitrile (4714-63-0)

Guidance literature:

N-(4-cyanophenyl)-N-ethylacetamide; With hydrogenchloride; water; for 4h; Reflux;

With potassium carbonate;

Reference yield:

N-(4-cyanophenyl)-N-ethylacetamide (155053-12-6) → 4-[ethyl(methyl)amino]benzenecarbothioamide (229970-83-6)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogenchloride; water / 4 h / Reflux

2: potassium carbonate / dimethyl sulfoxide / 36 h / 60 °C / In a sealed tube

3: methanol; tetraphosphorus decasulfide / 18 h / 20 °C / Inert atmosphere

With hydrogenchloride; methanol; tetraphosphorus decasulfide; water; potassium carbonate; In dimethyl sulfoxide;

upstream raw materials:

ethyl iodide

N-(4-cyanophenyl)acetamide

Downstream raw materials:

4-(ethylamino)benzonitrile

N-ethyl-N-methyl-4-cyanoaniline

4-[ethyl(methyl)amino]benzenecarbothioamide

2-{4-[ethyl(methyl)amino]phenyl}-4,5,6,7-tetrahydro-1,3-benzothiazol-7-ol

Refernces