2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester

Base Information

• Chemical Name: 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester
• CAS No.: 87670-08-4
• Molecular Formula: C₁₈H₂₅NO₄
• Molecular Weight: 319.401
• Mol file: 87670-08-4.mol

Synonyms:2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester

Chemical Property of 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester

There total 5 articles about 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H26ClNO4 (87669-82-7,87669-95-2) → 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester (87670-08-4)

Guidance literature:

With sodium ethanolate; In ethanol; at 40 ℃; for 1h;

DOI:10.1248/cpb.31.887

Reference yield:

L-glutamic acid diethyl ester (16450-41-2) → 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester (87670-08-4)

Guidance literature:

Multi-step reaction with 4 steps

1: benzene / 48 h / Heating

2: H₂ / 5percent palladium on charcoal / ethanol / 16 h / Ambient temperature

3: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C

4: sodium ethoxide / ethanol / 1 h / 40 °C

With tert-butylhypochlorite; hydrogen; sodium ethanolate; palladium on activated charcoal; In diethyl ether; ethanol; benzene;

DOI:10.1248/cpb.31.887

Reference yield:

(S)-2-[1-Methyl-2-phenyl-eth-(Z)-ylideneamino]-pentanedioic acid diethyl ester (59903-71-8) → 2-[(E)-1-Methyl-2-phenyl-ethylimino]-pentanedioic acid diethyl ester (87670-08-4)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / 5percent palladium on charcoal / ethanol / 16 h / Ambient temperature

2: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C

3: sodium ethoxide / ethanol / 1 h / 40 °C

With tert-butylhypochlorite; hydrogen; sodium ethanolate; palladium on activated charcoal; In diethyl ether; ethanol;

DOI:10.1248/cpb.31.887

upstream raw materials:

C₁₈H₂₆ClNO₄

L-glutamic acid diethyl ester

(S)-2-[1-Methyl-2-phenyl-eth-(Z)-ylideneamino]-pentanedioic acid diethyl ester

(S)-2-(1-Methyl-2-phenyl-ethylamino)-pentanedioic acid diethyl ester

Downstream raw materials:

(S)-N-(1-phenylprop-2-yl)benzamide

diethyl 2-ketoglutarate

dexamfetamine

l-amphetamine