(E)-N-((Pyridin-2-yl)methylene)benzenamine

Base Information

• Chemical Name: (E)-N-((Pyridin-2-yl)methylene)benzenamine
• CAS No.: 40468-86-8
• Molecular Formula: C₁₂H₁₀N₂
• Molecular Weight: 182.225
• Mol file: 40468-86-8.mol

Synonyms:trans-N-(2-Pyridylmethylene)aniline

Chemical Property of (E)-N-((Pyridin-2-yl)methylene)benzenamine

Chemical Property:

• Melting Point: 35-40 °C
• Boiling Point: 97-101/0.1 mmHg
• PKA: 2.47±0.50(Predicted)
• Flash Point: 110 °C
• PSA: 25.25000
• Density: 1.02±0.1 g/cm3(Predicted)
• LogP: 2.83220

Purity/Quality:

98%,99%, ^*data from raw suppliers

trans-N-(2-Pyridylmethylene)aniline 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36/37/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of (E)-N-((Pyridin-2-yl)methylene)benzenamine

There total 10 articles about (E)-N-((Pyridin-2-yl)methylene)benzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

pyridine-2-carbaldehyde (1121-60-4) + aniline (62-53-3) → (E)-N-(2-pyridylmethylene)aniline (7032-25-9,40468-86-8,88785-71-1)

Guidance literature:

In toluene; at 20 ℃; for 24h;

DOI:10.1039/b712901g

Reference yield:

(4-iodo-phenyl)-pyridin-2-ylmethylene-amine + aniline (62-53-3) → (E)-N-(2-pyridylmethylene)aniline (7032-25-9,40468-86-8,88785-71-1) + p-aminoiodobenzene (540-37-4)

Guidance literature:

In dimethylsulfoxide-d6; at 20 ℃; for 48h; Equilibrium constant;

DOI:10.1021/ja061841u

Reference yield:

4-{[1-Pyridin-2-yl-meth-(E)-ylidene]-amino}-benzoic acid ethyl ester (25100-42-9) + aniline (62-53-3) → (E)-N-(2-pyridylmethylene)aniline (7032-25-9,40468-86-8,88785-71-1) + p-aminoethylbenzoate (94-09-7)

Guidance literature:

In dimethylsulfoxide-d6; at 20 ℃; for 48h; Equilibrium constant;

DOI:10.1021/ja061841u

upstream raw materials:

Phenyl-[1-pyridin-2-yl-meth-(Z)-ylidene]-amine

pyridine-2-carbaldehyde

aniline

N-(p-dimethylaminophenyl)pyridine-2-aldimine

Downstream raw materials:

4-{[1-Pyridin-2-yl-meth-(E)-ylidene]-amino}-benzoic acid ethyl ester

aniline

pyridyl[1,2-a](2-phenylimidazol)-3-ylidene chloride

bis-(2-phenylpyridinecarboxaldimine)silver(I)perchlorate

Refernces

• 1、 Hotze, Anna C. G.,Faiz, Jonathan A.,Mourtzis, Nikolaos,Pascu, Gabriel I.,Webber, Philip R. A.,Clarkson, Guy J.,Yannakopoulou, Konstantina,Pikramenou, Zoe,Hannon, Michael J.. "Far-red luminescent ruthenium pyridylimine complexes; Building blocks for multinuclear arrays". . p. 3025 - 3034. Retrieved 2006.
• 2、 Pfeifer, Lukas,Gouverneur, Véronique. "Controlled Single and Double Iodofluorination of Alkynes with DIH- and HF-Based Reagents". supporting information. p. 1576 - 1579. Retrieved 2018/03/23.
• 3、 Park, Suhyun,Lee, Jaegyeong,Jeong, Jong Hwa,Lee, Hyosun,Nayab, Saira. "Palladium(II) complexes containing N,N′-bidentate imine ligands derived from picolinaldehyde and substituted anilines: Synthesis, structure and polymerisation of methyl methacrylate". . p. 82 - 89. Retrieved 2018/06/01.