(C₁₆H₁₂ClN₂O)Au(P(C₆H₅)3)

Base Information

• Chemical Name: (C₁₆H₁₂ClN₂O)Au(P(C₆H₅)3)
• CAS No.: 207515-11-5
• Molecular Formula: C₃₄H₂₇AuClN₂OP
• Molecular Weight: 742.994
• Mol file: 207515-11-5.mol

Synonyms:(C₁₆H₁₂ClN₂O)Au(P(C₆H₅)3)

Chemical Property of (C₁₆H₁₂ClN₂O)Au(P(C₆H₅)3)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (C₁₆H₁₂ClN₂O)Au(P(C₆H₅)3)

There total 1 articles about (C₁₆H₁₂ClN₂O)Au(P(C₆H₅)3) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

(triphenylphosphine)gold(I) chloride (14243-64-2) + diazepam (439-14-5) → (C16H12ClN2O)Au(P(C6H5)3) (207515-11-5)

Guidance literature:

With KOH; In ethanol; byproducts: KCl, H2O; dropwise addn. of 1.1 equiv. of KOH soln. to equimolar mixt. of Au-complex with ligand, stirring at room temp.; filtration, evapn., dissoln. in CH2Cl2, filtration, concn., pptn. on Et2O addn., recrystn. (CH2Cl2/Et2O); elem. anal.;

DOI:10.1016/S0022-328X(97)00624-4

Reference yield: 87.5%

(C16H12ClN2O)Au(P(C6H5)3) (207515-11-5) + bromine (7726-95-6) → bromo(triphenylphosphine)gold(I) (79384-10-4,14243-65-3)

Guidance literature:

In benzene; stirring equimolar amts. (cold water bath, 45 min); concn., pptn. on hexane addn., recrystn. (C6H6/hexane);

DOI:10.1016/S0022-328X(97)00624-4

Reference yield: 85.3%

silver tetrafluoroborate (14104-20-2) + (triphenylphosphine)gold(I) chloride (14243-64-2) + (C16H12ClN2O)Au(P(C6H5)3) (207515-11-5) → (C16H12ClN2O)[Au(P(C6H5)3)]2(1+)*BF4(1-)=[(C16H12ClN2O)[Au(P(C6H5)3)]2]BF4 (207515-20-6)

Guidance literature:

In methanol; byproducts: AgCl; addn. of equimolar amt. of AgBF4 to PPh3AuCl suspn., filtration off of AgCl, addn. of equimolar amt. of Au-diazepam complex, stirring (room temp., 5 h); evapn., dissoln. in CHCl3, filtration, concn., pptn. on Et2O addn., recrystn. (Me2CO/Et2O); elem. anal.;

DOI:10.1016/S0022-328X(97)00624-4

upstream raw materials:

(triphenylphosphine)gold(I) chloride

diazepam

Downstream raw materials:

(triphenylphosphine)gold(I) chloride

bromo(triphenylphosphine)gold(I)

(C₁₆H₁₂ClN₂O)[Au(P(C₆H₅)3)]2⁽¹⁺⁾*BF₄^(1-)=[(C₁₆H₁₂ClN₂O)[Au(P(C₆H₅)3)]2]BF₄

(C₁₉H₁₆ClN₂O)Au(P(C₆H₅)3)

Refernces