diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Base Information

Chemical Name:diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate
CAS No.:947695-27-4
Molecular Formula:C₂₄H₃₈N₂O₉
Molecular Weight:498.574
Hs Code.:

Synonyms:diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Suppliers and Price of diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

There total 6 articles about diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 947695-31-0
diisopropyl 1-{(1R)-1-[(4R,5S)-5-(ethoxycarbonyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

: 947695-27-4
diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Guidance literature:: With lithium borohydride; In tetrahydrofuran; ethanol; at 0 ℃;
DOI:10.1055/s-2007-966062

Reference yield:

: 947695-28-5
diisopropyl 1-{(1R)-1-formyl-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

: 947695-27-4
diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 4.35 g / benzene / 20 h / 6 °C

2: 74 percent / osmium tetroxide; N-methylmorpholine N-oxide / H₂O; acetone / 24 h / 20 °C

3: 88 percent / 10-camphorsulfonic acid / acetone / 2 h / 20 °C

4: 85 percent / lithium borohydride / ethanol; tetrahydrofuran / 0 °C

With osmium(VIII) oxide; lithium borohydride; (1S)-10-camphorsulfonic acid; 4-methylmorpholine N-oxide; In tetrahydrofuran; ethanol; water; acetone; benzene; 1: Wittig olefination;
DOI:10.1055/s-2007-966062

Reference yield:

: 947695-30-9
diisopropyl 1-{(1R,2R,3S)-4-ethoxy-2,3-dihydroxy-1-[(4-methoxybenzyl)oxy]methyl-4-oxobutyl}-1,2-hydrazinedicarboxylate

: 947695-27-4
diisopropyl 1-{(1R)-1-[(4R,5R)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]-2-[(4-methoxybenzyl)oxy]ethyl}-1,2-hydrazinedicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / 10-camphorsulfonic acid / acetone / 2 h / 20 °C

2: 85 percent / lithium borohydride / ethanol; tetrahydrofuran / 0 °C

With lithium borohydride; (1S)-10-camphorsulfonic acid; In tetrahydrofuran; ethanol; acetone;
DOI:10.1055/s-2007-966062