4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

Base Information

Chemical Name:4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine
CAS No.:405230-97-9
Molecular Formula:C6H3 Cl F N3
Molecular Weight:171.56
Hs Code.:2933998090
DSSTox Substance ID:DTXSID30573853
Wikidata:Q82462699
Mol file:405230-97-9.mol

Synonyms:4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine;405230-97-9;4-chloro-7-fluoro-3H-imidazo[4,5-c]pyridine;4-Chloro-7-fluoro-5H-imidazo[4,5-c]pyridine;1935570-37-8;SCHEMBL6307456;DTXSID30573853;MFCD18253397;AKOS025149614;DS-10386;CS-0157344

Suppliers and Price of 4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95.0%
100 mg
$ 248.00

SynQuest Laboratories
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95.0%
250 mg
$ 397.00

Crysdot
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
250mg
$ 318.00

Crysdot
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
1g
$ 794.00

Chemenu
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95%
1g
$ 750.00

Apolloscientific
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
250mg
$ 248.00

Apolloscientific
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
100mg
$ 155.00

Ambeed
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
250mg
$ 159.00

Ambeed
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
100mg
$ 106.00

Ambeed
4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95+%
1g
$ 395.00

Total 5 raw suppliers

Chemical Property of 4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

Chemical Property:

PSA：41.57000
LogP:1.75040
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:170.9999530
Heavy Atom Count:11
Complexity:157

Purity/Quality:

99%+ ^*data from raw suppliers

4-Chloro-7-fluoro-1H-imidazo[4,5-c]pyridine 95.0% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C2=C(C(=N1)Cl)NC=N2)F

Technology Process of 4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

There total 12 articles about 4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 14036-06-7
diethoxymethyl acetate

: 405230-93-5
2-chloro-3,4-diamino-5-fluoropyridine

: 405230-97-9
4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

: 405231-23-4
1-[(1-acetyloxy-1-ethoxy)methyl]-4-chloro-7-fluoroimidazo[4,5-c]pyridine

Guidance literature:: DOI:10.1081/NCN-100108327

Reference yield: 79.0%

: 122-51-0
orthoformic acid triethyl ester

: 405230-93-5
2-chloro-3,4-diamino-5-fluoropyridine

: 405230-97-9
4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

Guidance literature:: With aminosulfonic acid; In methanol; for 16h; Inert atmosphere; Reflux;

Reference yield:

: 31301-51-6
2-chloro-5-fluoropyridine

: 405230-97-9
4-chloro-7-fluoro-1H-imidazo[4,5-c]pyridine

Guidance literature:: Multi-step reaction with 7 steps

1: 3.6 g / TFA; aq. H₂O₂ / 20 h / 70 - 75 °C

2: 59 percent / conc. H₂SO₄; KNO₃ / 2 h / 120 °C

3: 91 percent / H₂ / Raney Ni / ethanol / 3 h / 2068.59 Torr

4: 83 percent / conc. H₂SO₄; KNO₃ / 0 - 20 °C

5: 90 percent / conc. H₂SO₄ / 20 °C

6: 94 percent / H₂ / Raney Ni / ethanol

With sulfuric acid; hydrogen; dihydrogen peroxide; potassium nitrate; trifluoroacetic acid; nickel; In ethanol;
DOI:10.1081/NCN-100108327