C₈H₁₀INO₂

Base Information

• Chemical Name: C₈H₁₀INO₂
• CAS No.: 874347-50-9
• Molecular Formula: C₈H₁₀INO₂
• Molecular Weight: 279.077
• Mol file: 874347-50-9.mol

Synonyms:C₈H₁₀INO₂

Chemical Property of C₈H₁₀INO₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₈H₁₀INO₂

There total 3 articles about C₈H₁₀INO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-iodo-2-methoxy-benzaldehyde (874347-49-6) → C8H10INO2 (874347-50-9)

Guidance literature:

3-iodo-2-methoxy-benzaldehyde; With potassium hydroxide; hydroxylamine hydrochloride; In tetrahydrofuran; methanol; water; at 20 ℃; for 16h; pH=9;

With hydrogenchloride; methyl orange; sodium cyanoborohydride; In tetrahydrofuran; methanol; water; for 16h; pH=2;

Reference yield:

C8H8INO2 → C8H10INO2 (874347-50-9)

Guidance literature:

C₈H₈INO₂; With hydrogenchloride; methyl orange; sodium cyanoborohydride; In tetrahydrofuran; methanol; water; for 16h; pH=2;

In tetrahydrofuran; methanol; water; pH=7; Alkaline aqueous solution;

Reference yield:

2-hydroxy-3-iodo-benzaldehyde (23602-64-4) → C8H10INO2 (874347-50-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 24 h / 0 - 20 °C

2.1: potassium hydroxide; hydroxylamine hydrochloride / tetrahydrofuran; methanol; water / 16 h / 20 °C / pH 9

3.1: hydrogenchloride; methyl orange; sodium cyanoborohydride / tetrahydrofuran; methanol; water / 16 h / pH 2

3.2: pH 7 / Alkaline aqueous solution

With hydrogenchloride; potassium hydroxide; hydroxylamine hydrochloride; methyl orange; sodium hydride; sodium cyanoborohydride; In tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;

upstream raw materials:

3-iodo-2-methoxy-benzaldehyde

2-hydroxy-3-iodo-benzaldehyde

Downstream raw materials:

C₁₁H₁₂INO₄

C₁₆H₂₀INO₇S

C₁₁H₁₂INO₄

C₅₃H₈₂N₆O₉SSi