4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine

Base Information

• Chemical Name: 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine
• CAS No.: 108237-91-8
• Molecular Formula: C₁₅H₁₁BrN₂S
• Molecular Weight: 331.236
• Mol file: 108237-91-8.mol

Synonyms:4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine

Chemical Property of 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine

Chemical Property:

Purity/Quality:

99.90% ^*data from raw suppliers

RCGD423 ≥98%(HPLC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine

There total 6 articles about 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-(4-bromophenyl)thiourea (2646-30-2) + α-bromoacetophenone (70-11-1) → 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine (108237-91-8)

Guidance literature:

In ethanol; at 80 ℃; under 1500.15 Torr;

Reference yield: 98.0%

→ 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine (108237-91-8)

Guidance literature:

In ethanol; at 80 ℃;

Reference yield: 82.0%

1-(4-bromophenyl)thiourea (2646-30-2) + acetophenone (98-86-2) → 4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine (108237-91-8)

Guidance literature:

With carbon tetrabromide; triethylamine; In acetonitrile; at 20 ℃; for 4h;

DOI:10.1016/j.tetlet.2015.08.064

upstream raw materials:

1-(4-bromophenyl)thiourea

acetophenone

α-bromoacetophenone

acetophenone O-acetyloxime

Downstream raw materials:

4-phenyl-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiazol-2-amine

4-(4-((4-phenylthiazol-2-yl)amino)phenyl)phthalazin-1(2H)-one