2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline

Base Information

Chemical Name:2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline
CAS No.:1424336-77-5
Molecular Formula:C₁₇H₁₅ClFN₃O₄S
Molecular Weight:411.841
Hs Code.:

Synonyms:2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline

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Chemical Property of 2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline

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Technology Process of 2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline

There total 1 articles about 2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 832755-13-2
2-fluoro-4-methanesulfonylaniline

: 27631-29-4
2-chloro-6,7-dimethoxy-3H-quinazolin-4-one

: 1424336-77-5
2-chloro-4-(2-fluoro-4-methylsulfonylphenylamino)-6,7-dimethoxyquinazoline

Guidance literature:: 2-fluoro-4-methanesulfonylaniline; With sodium hydride; In tetrahydrofuran; for 1h; Inert atmosphere;

2-chloro-6,7-dimethoxy-3H-quinazolin-4-one; In tetrahydrofuran; Inert atmosphere; Reflux;
DOI:10.1016/j.bmc.2012.12.013