2-[(Dimethylamino)methyl]-4-fluorophenol

Base Information

• Chemical Name: 2-[(Dimethylamino)methyl]-4-fluorophenol
• CAS No.: 46049-91-6
• Molecular Formula: C9H12 F N O
• Molecular Weight: 169.2
• Hs Code.: 2922299090
• European Community (EC) Number: 642-680-7
• DSSTox Substance ID: DTXSID60442361
• Mol file: 46049-91-6.mol

Synonyms:46049-91-6;2-[(dimethylamino)methyl]-4-fluorophenol;5-fluoro-2-hydroxy-n,n-dimethylbenzylamine;2-Dimethylaminomethyl-4-fluoro-phenol;2-((Dimethylamino)methyl)-4-fluorophenol;MFCD03412238;n,n-dimethyl-2-hydroxy-5-fluorobenzylamine;SCHEMBL5804362;DTXSID60442361;AKOS005254315;PS-6848;CS-0317752;FT-0691504;2-[(dimethylamino)methyl]-4-fluoranyl-phenol;A826977;5-fluoro-2-hydroxy-N,N-dimethylbenzylamine, AldrichCPR

Chemical Property of 2-[(Dimethylamino)methyl]-4-fluorophenol

Chemical Property:

• Vapor Pressure: 0.06mmHg at 25°C
• Refractive Index: 1.532
• Boiling Point: 224.6°Cat760mmHg
• Flash Point: 89.7°C
• PSA: 23.47000
• Density: 1.138g/cm³
• LogP: 1.59290
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 169.090292168
• Heavy Atom Count: 12
• Complexity: 141

Purity/Quality:

97% ^*data from raw suppliers

5-Fluoro-2-hydroxy-N,N-dimethylbenzylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC1=C(C=CC(=C1)F)O

Technology Process of 2-[(Dimethylamino)methyl]-4-fluorophenol

There total 2 articles about 2-[(Dimethylamino)methyl]-4-fluorophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-Fluorophenol (371-41-5) + dimethyl amine (124-40-3) → 2,6-di-(dimethyl amino)-methyl-4-fluorophenol (262596-90-7) + N,N-dimethyl-2-hydroxy-5-fluorobenzylamine (46049-91-6)

Guidance literature:

In water; at 10 ℃; for 20h;

DOI:10.1080/00397910008087335

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-Fluorophenol (371-41-5) + dimethyl amine (124-40-3) → N,N-dimethyl-2-hydroxy-5-fluorobenzylamine (46049-91-6)

Guidance literature:

In water; at 20 ℃; Inert atmosphere;

DOI:10.1002/jhet.1964

Reference yield: 62.0%

4-chloro-3-nitrobenzonitrile (939-80-0) + N,N-dimethyl-2-hydroxy-5-fluorobenzylamine (46049-91-6) → N,N-dimethyl-2-(4-cyano-2-nitrophenyloxy)-5-fluorobenzylamine

Guidance literature:

N,N-dimethyl-2-hydroxy-5-fluorobenzylamine; With potassium hydroxide; at 20 ℃; for 0.5h;

4-chloro-3-nitrobenzonitrile; In dimethyl sulfoxide; at 160 ℃; for 8h; Further stages.;

DOI:10.1016/j.bmcl.2007.02.082

upstream raw materials:

formaldehyd

4-Fluorophenol

dimethyl amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 46049-91-6 2-DIMETHYLAMINOMETHYL-4-FLUORO-PHENOL

Send

Send

Metric Ton KG G Pound L ML

Send

Send