isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Base Information

Chemical Name:isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate
CAS No.:1445791-02-5
Molecular Formula:C₂₃H₂₃BrFN₃O₄
Molecular Weight:504.356
Hs Code.:

Synonyms:isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Suppliers and Price of isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

There total 8 articles about isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1445790-73-7
7-bromo-4-chloro-8-fluoroquinoline-3-carboxamide

: 1394973-92-2
isopropyl 3-amino-5-isopropoxybenzoate

: 1445791-02-5
isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Guidance literature:: With acetic acid; at 20 ℃; for 16h;

Reference yield:

: 58534-95-5
3-bromo-2-fluorobenzenamine

: 1445791-02-5
isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1 h / 100 °C

2.1: diphenylether / 16 h / 240 °C

3.1: potassium hydroxide; water / tetrahydrofuran; methanol / 20 h / 45 °C

4.1: trichlorophosphate / 3 h / 110 °C

4.2: Cooling with ice

5.1: acetic acid / 16 h / 20 °C

With water; acetic acid; potassium hydroxide; trichlorophosphate; In tetrahydrofuran; methanol; diphenylether;

Reference yield:

: 1445790-67-9
diethyl 2-(((3-bromo-2-fluorophenyl)amino)methylene)malonate

: 1445791-02-5
isopropyl 3-((7-bromo-3-carbamoyl-8-fluoroquinolin-4-yl)amino)-5-isopropoxybenzoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: diphenylether / 16 h / 240 °C

2.1: potassium hydroxide; water / tetrahydrofuran; methanol / 20 h / 45 °C

3.1: trichlorophosphate / 3 h / 110 °C

3.2: Cooling with ice

4.1: acetic acid / 16 h / 20 °C

With water; acetic acid; potassium hydroxide; trichlorophosphate; In tetrahydrofuran; methanol; diphenylether;