RARECHEM AL BE 0983

Base Information

• Chemical Name: RARECHEM AL BE 0983
• CAS No.: 50472-09-8
• Molecular Formula: C₉H₉NO₆
• Molecular Weight: 227.174
• Mol file: 50472-09-8.mol

Synonyms:3,6-dimethoxy-2-nitrobenzoic acid

Chemical Property of RARECHEM AL BE 0983

Chemical Property:

• Melting Point: 192-193 °C (decomp)
• Boiling Point: 427.5±45.0 °C(Predicted)
• PKA: 1.78±0.30(Predicted)
• Density: 1.403±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

3,6-Dimethoxy-2-nitrobenzoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of RARECHEM AL BE 0983

There total 8 articles about RARECHEM AL BE 0983 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,5-dimethoxy-6-nitrobenzamide (26002-58-4) → 3,6-dimethoxy-2-nitrobenzoic acid (50472-09-8)

Guidance literature:

With sulfuric acid; sodium nitrite; for 15h; Ambient temperature;

DOI:10.1016/0040-4020(95)00354-B

Reference yield: 88.0%

2,5-dimethoxybenzoic acid (2785-98-0) → 3,6-dimethoxy-2-nitrobenzoic acid (50472-09-8)

Guidance literature:

With nitric acid; at 0 - 2 ℃; for 0.5h;

Reference yield: 76.0%

2,5-dimethoxybenzoic acid (2785-98-0) → 3,6-dimethoxy-2-nitrobenzoic acid (50472-09-8) + 2,5-dimethoxy-3-nitro-benzoic acid (17894-26-7)

Guidance literature:

With nitric acid;

DOI:10.1080/00397919908086212

upstream raw materials:

2,5-dimethoxybenzoic acid

6-hydroxy-3-methoxy-2-nitrobenzoic acid

dimethyl sulfate

2,5-dimethoxy-6-nitrobenzamide

Downstream raw materials:

2-amino-3,6-dimethoxybenzoic acid

3,6-dimethoxy-2-nitrobenzoyl chloride

3,6-dimethoxyl-2-methylbenzaldehyde

2-Carboxy-3,6-dimethoxy-benzenediazonium; chloride