3-Amino-5-hydroxy-4-methoxybenzaldehyde

Base Information

Chemical Name:3-Amino-5-hydroxy-4-methoxybenzaldehyde
CAS No.:343867-62-9
Molecular Formula:C₈H₉NO₃
Molecular Weight:167.164
Hs Code.:2922509090
DSSTox Substance ID:DTXSID80513188
Wikidata:Q82372851
Mol file:343867-62-9.mol

Synonyms:3-amino-5-hydroxy-4-methoxybenzaldehyde;343867-62-9;DTXSID80513188

Suppliers and Price of 3-Amino-5-hydroxy-4-methoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Amino-5-hydroxy-4-methoxybenzaldehyde

Chemical Property:

PSA：72.55000
LogP:1.37670
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:167.058243149
Heavy Atom Count:12
Complexity:162

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1O)C=O)N

Technology Process of 3-Amino-5-hydroxy-4-methoxybenzaldehyde

There total 1 articles about 3-Amino-5-hydroxy-4-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80547-69-9
3-hydroxy-4-methoxy-5-nitrobenzaldehyde

: 343867-62-9
3-Amino-5-hydroxy-4-methoxy-benzaldehyde

Guidance literature:: With hydrogenchloride; tin(ll) chloride; at 0 - 65 ℃;
DOI:10.1021/jm00345a012

Reference yield:

: 343867-62-9
3-Amino-5-hydroxy-4-methoxy-benzaldehyde

: 54246-06-9
3-chloro-5-hydroxy-4-methoxybenzaldehyde

Guidance literature:: With copper(l) chloride; sodium nitrite; Yield given. Multistep reaction; 1.) H₂O, from 0 to 5 deg C, 1.5 h, 2.) H₂O, from 75 deg C to RT, overnight;
DOI:10.1021/jm00345a012

Reference yield:

: 343867-62-9
3-Amino-5-hydroxy-4-methoxy-benzaldehyde

: 80547-63-3
3-chloro-5-hydroxy-4-methoxybenzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 23percent NaNO₂, CuCl / 1.) H₂O, from 0 to 5 deg C, 1.5 h, 2.) H₂O, from 75 deg C to RT, overnight

2: 50 percent / AgNO₃, aq. NaOH / 0.25 h / 55 °C

With sodium hydroxide; silver nitrate; copper(l) chloride; sodium nitrite;
DOI:10.1021/jm00345a012