3-Chloro-5-hydroxy-4-methoxybenzaldehyde

Base Information

Chemical Name:3-Chloro-5-hydroxy-4-methoxybenzaldehyde
CAS No.:54246-06-9
Molecular Formula:C8H7ClO3
Molecular Weight:186.59238
Hs Code.:2913000090
ChEMBL ID:CHEMBL89349
DSSTox Substance ID:DTXSID101275186
Mol file:54246-06-9.mol

Synonyms:3-chloro-5-hydroxy-4-methoxybenzaldehyde;54246-06-9;Benzaldehyde, 3-chloro-5-hydroxy-4-methoxy-;CHEMBL89349;SCHEMBL2808932;DTXSID101275186;MFCD01191266;BS-49982;3-Chloro-5-hydroxy-4-methoxy-benzaldehyde;CS-0150569;E76289

Suppliers and Price of 3-Chloro-5-hydroxy-4-methoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Chloro-5-hydroxy-4-methoxybenzaldehyde 95+%
1g
$ 518.00

Alichem
3-Chloro-5-hydroxy-4-methoxybenzaldehyde
1g
$ 455.76

Activate Scientific
3-Chloro-5-hydroxy-4-methoxybenzaldehyde 95%
250 mg
$ 224.00

Total 7 raw suppliers

Chemical Property of 3-Chloro-5-hydroxy-4-methoxybenzaldehyde

Chemical Property:

PSA：46.53000
LogP:1.86670
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:186.0083718
Heavy Atom Count:12
Complexity:162

Purity/Quality:

99% ^*data from raw suppliers

3-Chloro-5-hydroxy-4-methoxybenzaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=C(C=C1Cl)C=O)O

Technology Process of 3-Chloro-5-hydroxy-4-methoxybenzaldehyde

There total 6 articles about 3-Chloro-5-hydroxy-4-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 511295-05-9
5-chloro-O-acetyl isovanilline

: 54246-06-9
3-chloro-5-hydroxy-4-methoxybenzaldehyde

Guidance literature:: With sodium hydroxide; for 2h; Heating;
DOI:10.1055/s-2002-35629

Reference yield:

: 621-59-0
isovanillin

: 54246-06-9
3-chloro-5-hydroxy-4-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / 1 h / Heating

2: 79 percent / N,N'-dichloropiperazine / aq. H₂SO₄ / 1 h / 20 °C

3: 95 percent / aq. NaOH / 2 h / Heating

With N,N'-dichloropiperazine; sodium hydroxide; In sulfuric acid;
DOI:10.1055/s-2002-35629

Reference yield:

: 881-57-2
isovanillin acetate

: 54246-06-9
3-chloro-5-hydroxy-4-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / N,N'-dichloropiperazine / aq. H₂SO₄ / 1 h / 20 °C

2: 95 percent / aq. NaOH / 2 h / Heating

With N,N'-dichloropiperazine; sodium hydroxide; In sulfuric acid;
DOI:10.1055/s-2002-35629