1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Base Information

Chemical Name:1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine
CAS No.:159227-96-0
Molecular Formula:C₄₄H₃₈N₄O₈S
Molecular Weight:782.874
Hs Code.:

Synonyms:1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Suppliers and Price of 1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

There total 12 articles about 1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 124-63-0
methanesulfonyl chloride

: 159227-95-9
1-(2-deoxy-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

: 159227-96-0
1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Guidance literature:: In pyridine; for 2h; Ambient temperature;
DOI:10.1080/15257779408013278

Reference yield:

: 50255-88-4
6,7-diphenyl-2,4-bis-trimethylsilanyloxy-pteridine

: 159227-96-0
1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Guidance literature:: Multi-step reaction with 7 steps

1: BF₃*OEt₂ / ethyl acetate / 2 h / Ambient temperature

2: 72 percent / pyridine, acetic acid, hydrazine monohydrate / 22 h / Ambient temperature

3: 92 percent / DMAP / acetonitrile / 0.17 h

4: 73 percent / AIBN, n-Bu₃SnH / toluene / 1.5 h / Heating

5: 84 percent / sodium methoxide

6: 69 percent / pyridine

7: 84 percent / pyridine / 2 h / Ambient temperature

With pyridine; dmap; 2,2'-azobis(isobutyronitrile); boron trifluoride diethyl etherate; tri-n-butyl-tin hydride; sodium methylate; hydrazine hydrate; acetic acid; In pyridine; ethyl acetate; toluene; acetonitrile;
DOI:10.1080/15257779408013278

Reference yield:

: 14892-98-9
6,7-diphenylpteridine-2,4(1H,3H)-dione

: 159227-96-0
1-(2-deoxy-3-O-mesyl-5-O-p-monomethoxytrityl-β-D-threo-pentofuranosyl)-6,7-diphenyllumazine

Guidance literature:: Multi-step reaction with 8 steps

1: ammonium sulfate / Heating

2: BF₃*OEt₂ / ethyl acetate / 2 h / Ambient temperature

3: 72 percent / pyridine, acetic acid, hydrazine monohydrate / 22 h / Ambient temperature

4: 92 percent / DMAP / acetonitrile / 0.17 h

5: 73 percent / AIBN, n-Bu₃SnH / toluene / 1.5 h / Heating

6: 84 percent / sodium methoxide

7: 69 percent / pyridine

8: 84 percent / pyridine / 2 h / Ambient temperature

With pyridine; dmap; ammonium sulfate; 2,2'-azobis(isobutyronitrile); boron trifluoride diethyl etherate; tri-n-butyl-tin hydride; sodium methylate; hydrazine hydrate; acetic acid; In pyridine; ethyl acetate; toluene; acetonitrile;
DOI:10.1080/15257779408013278