(2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Base Information

Chemical Name:(2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane
CAS No.:261968-10-9
Molecular Formula:C₂₇H₅₂O₃Si₂
Molecular Weight:480.879
Hs Code.:

Synonyms:(2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Suppliers and Price of (2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

There total 8 articles about (2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 69739-34-0
t-butyldimethylsiyl triflate

: 261968-09-6
(2S,3R,4S,5S)-1-benzyloxy-2,4-dimethylhexane-3,5-diol

: 261968-10-9
(2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; at -78 ℃; for 2h;
DOI:10.1002/(SICI)1521-3773(20000117)39:2<377::AID-ANIE377>3.0.CO;2-E

Reference yield:

: 116546-78-2
(S)-1-benzyloxy-2-methylpentan-3-one

: 261968-10-9
(2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Guidance literature:: Multi-step reaction with 4 steps

1.1: Et₃N / diethyl ether / 2 h / 0 °C

2.1: diethyl ether / 23 h / -78 - -20 °C

3.1: lithium borohydride / diethyl ether; tetrahydrofuran / 3 h / -78 °C

3.2: 30percent aq. H₂O₂; 10percent aq. NaOH / methanol / 0 - 20 °C

4.1: 99 percent / 2,6-lutidine / CH₂Cl₂ / 2 h / -78 °C

With 2,6-dimethylpyridine; lithium borohydride; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja011211m

Reference yield:

: 152192-50-2
C₂₅H₃₉BO₂

: 261968-10-9
(2S,3R,4S,5S)-1-benzyloxy-3,5-bis-(t-butyldimethylsilyloxy)-2,4-dimethylhexane

Guidance literature:: Multi-step reaction with 3 steps

1.1: diethyl ether / 23 h / -78 - -20 °C

2.1: lithium borohydride / diethyl ether; tetrahydrofuran / 3 h / -78 °C

2.2: 30percent aq. H₂O₂; 10percent aq. NaOH / methanol / 0 - 20 °C

3.1: 99 percent / 2,6-lutidine / CH₂Cl₂ / 2 h / -78 °C

With 2,6-dimethylpyridine; lithium borohydride; In tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1021/ja011211m