(+/-)-(2-aminophenyl)methylphenylphosphine

Base Information

• Chemical Name: (+/-)-(2-aminophenyl)methylphenylphosphine
• CAS No.: 140669-67-6
• Molecular Formula: C₁₃H₁₄NP
• Molecular Weight: 215.235
• Mol file: 140669-67-6.mol

Synonyms:(+/-)-(2-aminophenyl)methylphenylphosphine

Chemical Property of (+/-)-(2-aminophenyl)methylphenylphosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-(2-aminophenyl)methylphenylphosphine

There total 10 articles about (+/-)-(2-aminophenyl)methylphenylphosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(+/-)-(2-Aminophenyl)phenylphosphine (67405-21-4) + methyl iodide (74-88-4) → (+/-)-(2-aminophenyl)methylphenylphosphine (140669-67-6)

Guidance literature:

With sodium; In tetrahydrofuran; 1.) 3 h, 2.) -78 deg C to r.t., overnight;

Reference yield:

(2-diphenylphosphino)benzeneamine (65423-44-1) → (+/-)-(2-aminophenyl)methylphenylphosphine (140669-67-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / Li, H₂O / tetrahydrofuran

2: 90 percent / Na / tetrahydrofuran / 1.) 3 h, 2.) -78 deg C to r.t., overnight

With water; sodium; lithium; In tetrahydrofuran;

Reference yield:

o-chloroaniline (95-51-2) → (+/-)-(2-aminophenyl)methylphenylphosphine (140669-67-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 57 percent / NiCl₂ / 4 h / 200 - 220 °C

2: sodium naphthalenide / tetrahydrofuran / 1 h

3: 93 percent / tetrahydrofuran / 3 h / Heating

4: sodium naphthalenide / tetrahydrofuran / 1 h

With sodium naphthalenide; nickel dichloride; In tetrahydrofuran;

upstream raw materials:

(2-Amino-phenyl)-methyl-diphenyl-phosphonium; iodide

(+/-)-(2-Aminophenyl)phenylphosphine

methyl iodide

(2-diphenylphosphino)benzeneamine

Downstream raw materials:

(+/-)[SP-4-2]-[(2-aminophenyl)methylphenylphosphine-N,P]dichloropalladium(II)

(+/-)[SP-4-2]-[(2-aminophenyl)methylphenylphosphine-N,P]dichloroplatinum(II)

(T-4)-bis[(+/-)-(2-aminophenyl)methylphenylphosphine]copper(I) hexafluorophosphate

(T-4)-tris[(+/-)(2-aminophenyl)methylphenylphosphine]copper(I) hexafluorophosphate