1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

Base Information

Chemical Name:1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol
CAS No.:1361221-44-4
Molecular Formula:C₁₅H₂₀BF₃O₃
Molecular Weight:316.128
Hs Code.:

Synonyms:1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

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Chemical Property of 1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

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Technology Process of 1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

There total 2 articles about 1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 122243-28-1
2‐(4‐bromophenyl)‐1,1,1‐trifluoropropan‐2‐ol

: 73183-34-3
bis(pinacol)diborane

: 1361221-44-4
1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; water; at 100 ℃; for 18h;
DOI:10.1021/jm5018175

Reference yield:

: 1361221-44-4
1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

Guidance literature:

Reference yield: 58.0%

: 1361221-44-4
1,1,1-trifluoro-2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propan-2-ol

: 53857-59-3
2,5-dibromo-1-methyl-1H-imidazole

: 2-(4-(5-bromo-1-methyl-1H-imidazol-2-yl)phenyl)-1,1,1-trifluoropropan-2-ol

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In 1,4-dioxane; water; at 100 ℃; for 5h; Inert atmosphere;
DOI:10.1021/jm5018175