4 6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL

Base Information

Chemical Name:4 6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL
CAS No.:312623-79-3
Molecular Formula:C14H16 O5
Molecular Weight:264.278
Hs Code.:
Mol file:312623-79-3.mol

Synonyms:4,6-O-P-METHOXYLBENZYLIDENE-D-GLUCAL;4,6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL;

Suppliers and Price of 4 6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4,6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL 95+%
1g
$ 329.00

Alfa Aesar
4,6-O-(4-Methoxybenzylidene)-D-glucal, 97%
1g
$ 91.30

Alfa Aesar
4,6-O-(4-Methoxybenzylidene)-D-glucal, 97%
250mg
$ 28.40

Total 3 raw suppliers

Chemical Property of 4 6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL

Chemical Property:

Melting Point:120-138 °C(lit.)
Boiling Point:276-289 °C(lit.)
PSA：57.15000
LogP:1.38260

Purity/Quality:

95% ^*data from raw suppliers

4,6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4,6-O-(4-Methoxybenzylidene)-D-glucal is used as pharmaceutical intermediate.

Technology Process of 4 6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL

There total 3 articles about 4 6-O-(4-METHOXYBENZYLIDENE)-D-GLUCAL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 2403-58-9
4-methoxybenzaldehyde diethylacetal

: 13265-84-4
D-glucal

: 312623-79-3
(4aR,8R,8aS)-2-(4-methoxyphenyl)-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxin-8-ol

Guidance literature:: With pyridinium p-toluenesulfonate; In N,N-dimethyl-formamide; at 25 ℃; for 2h; Reduced pressure;
DOI:10.1002/chem.200902048

Reference yield: 78.0%

: 2186-92-7
p-Anisaldehyde dimethyl acetal

: 13265-84-4
D-glucal

: 312623-79-3
(4aR,8R,8aS)-2-(4-methoxyphenyl)-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxin-8-ol

Guidance literature:: With pyridinium p-toluenesulfonate; In N,N-dimethyl-formamide; at 20 ℃; for 3h; Reduced pressure;

Reference yield:

: 2873-29-2
D-glucal triacetate

: 312623-79-3
(4aR,8R,8aS)-2-(4-methoxyphenyl)-4,4a,8,8a-tetrahydropyrano[3,2-d][1,3]dioxin-8-ol

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; potassium carbonate / 5 h / 23 °C / Inert atmosphere

2: pyridinium p-toluenesulfonate / tetrahydrofuran / 2 h / 23 °C / Inert atmosphere

With methanol; pyridinium p-toluenesulfonate; potassium carbonate; In tetrahydrofuran;
DOI:10.1021/acs.orglett.8b03228