2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide

Base Information

• Chemical Name: 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide
• CAS No.: 1139567-74-0
• Molecular Formula: C₁₆H₂₂BrNO₄S
• Molecular Weight: 404.325
• Mol file: 1139567-74-0.mol

Synonyms:2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide

Chemical Property of 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide

There total 3 articles about 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

2-bromo-4,5-dimethoxybenzene-1-sulfonyl chloride (51072-64-1) + 2-(1-cyclohexenyl)ethylamine (3399-73-3) → 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide (1139567-74-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/j.tetlet.2008.10.004

Reference yield:

C8H9BrO5S → 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide (1139567-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride / dichloromethane / 40 °C

2: triethylamine / dichloromethane / 0 - 20 °C

With thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1021/jo401888f

Reference yield:

4-Bromoveratrole (2859-78-1) → 2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxybenzenesulfonamide (1139567-74-0)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorosulfonic acid / dichloromethane / 0 °C

2: thionyl chloride / dichloromethane / 40 °C

3: triethylamine / dichloromethane / 0 - 20 °C

With chlorosulfonic acid; thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1021/jo401888f

upstream raw materials:

2-bromo-4,5-dimethoxybenzene-1-sulfonyl chloride

2-(1-cyclohexenyl)ethylamine

4-Bromoveratrole

Downstream raw materials:

2-bromo-N-(2-cyclohex-1-enylethyl)-4,5-dimethoxy-N-methylbenzenesulfonamide

1-(2-bromo-4,5-dimethoxybenzenesulfonyl)-2,4,5,6,7,7a-hexahydro-1H-indole