Technology Process of (-)-englerin B acetate
There total 6 articles about (-)-englerin B acetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: water; sodium periodate; sodium hydrogensulfite / acetonitrile / 0.5 h / 50 °C / Inert atmosphere
2.1: triethylamine / toluene / 0.17 h / 20 °C / Inert atmosphere
2.2: 4 h / 80 °C / Inert atmosphere
3.1: acetic acid / 4 h / 100 °C / Inert atmosphere
With
sodium periodate; water; sodium hydrogensulfite; acetic acid; triethylamine;
In
toluene; acetonitrile;
DOI:10.1016/j.tetlet.2014.01.012
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tetrahydrofuran; diethyl ether / 1 h / -20 °C / Inert atmosphere
2.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 1 h / 20 - 40 °C / Inert atmosphere
3.1: water; sodium periodate; sodium hydrogensulfite / acetonitrile / 0.5 h / 50 °C / Inert atmosphere
4.1: triethylamine / toluene / 0.17 h / 20 °C / Inert atmosphere
4.2: 4 h / 80 °C / Inert atmosphere
5.1: acetic acid / 4 h / 100 °C / Inert atmosphere
With
tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; sodium periodate; water; sodium hydrogensulfite; acetic acid; triethylamine;
In
tetrahydrofuran; diethyl ether; dichloromethane; toluene; acetonitrile;
DOI:10.1016/j.tetlet.2014.01.012
