(-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Base Information

Chemical Name:(-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide
CAS No.:623571-23-3
Molecular Formula:C₂₃H₂₉N₃O₅S₂
Molecular Weight:491.632
Hs Code.:

Synonyms:(-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Suppliers and Price of (-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

There total 7 articles about (-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 623571-45-9
(+)-(2R,3R)-3-hydroxy-9-[(4-methylphenyl)sulfonyl]-2-phenyl-1,5,9-triazacyclotridecan-4-one

: 623571-23-3
(-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Guidance literature:: With 1H-imidazole; thionyl chloride; In dichloromethane; at 5 ℃; for 0.5h;
DOI:10.1002/hlca.200390160

Reference yield:

: 78521-64-9
N-(4-aminobutyl)-4-methyl benzenesulfonamide

: 623571-23-3
(-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Guidance literature:: Multi-step reaction with 4 steps

1: 82.6 percent / CH₂Cl₂ / 0.42 h

2: Cs₂CO₃ / dimethylformamide / 7 h / 20 °C

3: 85 percent / aq. Na₂CO₃ / propan-2-ol / 36 h / 70 °C

4: 100 percent / 1H-imidazole; SOCl₂ / CH₂Cl₂ / 0.5 h / 5 °C

With 1H-imidazole; thionyl chloride; sodium carbonate; caesium carbonate; In dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1002/hlca.200390160

Reference yield:

: 186179-24-8
1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate

: 623571-23-3
(-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide

Guidance literature:: Multi-step reaction with 4 steps

1: 87.9 percent / CF₃COOH / CH₂Cl₂ / 17 h / 20 °C

2: Cs₂CO₃ / dimethylformamide / 7 h / 20 °C

3: 85 percent / aq. Na₂CO₃ / propan-2-ol / 36 h / 70 °C

4: 100 percent / 1H-imidazole; SOCl₂ / CH₂Cl₂ / 0.5 h / 5 °C

With 1H-imidazole; thionyl chloride; sodium carbonate; caesium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1002/hlca.200390160