186179-24-8

Basic information

• Product Name: 1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate
• Synonyms: 1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate
• CAS NO: 186179-24-8
• Molecular Weight: 342.459
• Mol File: 186179-24-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate(186179-24-8)
• EPA Substance Registry System: 1,1-dimethylethyl {4-{[(4-methylphenyl)sulfonyl]amino}butyl}carbamate(186179-24-8)

Safety Data

• Hazardous Substances Data: 186179-24-8(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 78521-64-9 N-(4-aminobutyl)-4-methyl benzenesulfonamide 
• 68076-36-8 1-amino-4-[(tert-butyloxycarbonyl)amino]butane 

Downstream Products

• 186179-28-2 Toluene-4-sulfonic acid 3-[tert-butoxycarbonyl-(4-tert-butoxycarbonylamino-butyl)-amino]-propyl ester 
• 186179-26-0 {4-[(3-Hydroxy-propyl)-(toluene-4-sulfonyl)-amino]-butyl}-carbamic acid tert-butyl ester 
• 422565-32-0 (S)-5,9-bis[(4-methylphenyl)sulfonyl]-4-phenyl-1,5,9-triazacyclotridecan-2-one 
• 422565-31-9 (S)-3-[(4-methylphenyl)sulfonylamino]-N-{4-[(4-methylphenyl)sulfonyl]aminobutyl}-3-phenylpropanamide 
• 623571-21-1 (+)-(2S,3S)-N-{3-{[(4-methylphenyl)sulfonyl]{4-[(trifluoroacetyl)amino]butyl}amino}propyl}-3-phenyloxiranecarboxamide 
• 623571-39-1 (+)-(2R,3S)-N-{3-{[(4-methylphenyl)sulfonyl]{4-[(trifluoroacetyl)amino]butyl}amino}propyl}-3-phenyloxiranecarboxamide 
• 623571-24-4 (-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14,14-dioxide 
• 623571-23-3 (-)-(12R,15R)-6-[(4-methylphenyl)sulfonyl]-15-phenyl-13-oxa-14-thia-1,6,10-triazabicyclo[10.2.1]pentadecan-11-one 14-oxide 
• 623571-26-6 (-)-(2R,3S)-3-hydroxy-9-[(4-methylphenyl)sulfonyl]-2-phenyl-1,5,9-triazatridecan-4-one 
• 623571-45-9 (+)-(2R,3R)-3-hydroxy-9-[(4-methylphenyl)sulfonyl]-2-phenyl-1,5,9-triazacyclotridecan-4-one 
• 623571-06-2 2,2,2-trifluoro-N-{4-{[(4-methylphenyl)sulfonyl]amino}butyl}acetamide 

Relevant articles and documents

A novel synthesis of the macrocyclic spermidine alkaloid (+)-(S)-dihydroperiphylline

A novel, short, and highly stereoselective synthesis of the macrocyclic spermidine alkaloid (+)-(S)-dihydroperiphylline (15) is described. The key synthetic steps were the stereoselective addition of the chiral amine 1 to the cinnamate 2 and cyclization o

178. Electrospray-ionization mass spectrometry part III: Acid-catalyzed isomerization of N,N′-bis[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]spermidines by the Zip reaction

The electrospray tandem mass spectra (ESI-MS/MS) of the three N,N′-bis[(E)-3-(4-hydroxyphenyl)prop-2-enoyl]spermidines 1-3 displayed the same fragment-ion signals. These isomers could not be differentiated by ESI-MS/MS, since their fragmentation patterns are similar. (E,E)-N-(3-[ 15N]Aminopropyl)-3,3′-bis(4-hydroxyphenyl)-N,N′-(butane- 1,4-diyl)bis[prop-2-enamide] ([15N(1)]-1) was synthesized in order to get further information about the fragmentation mechanisms. The comparison of the ESI-MS/MS of 1 and [15N(1)]-1 revealed a transamidation, the Zip reaction, under mass-spectral conditions of the [1 + H]+ ions. Because of this reaction, the three isomers 1-3 could not be distinguished.