C₃₀H₂₅Cl₃N₂O₆S

Base Information

• Chemical Name: C₃₀H₂₅Cl₃N₂O₆S
• CAS No.: 1370637-75-4
• Molecular Formula: C₃₀H₂₅Cl₃N₂O₆S
• Molecular Weight: 647.963
• Mol file: 1370637-75-4.mol

Synonyms:C₃₀H₂₅Cl₃N₂O₆S

Chemical Property of C₃₀H₂₅Cl₃N₂O₆S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₅Cl₃N₂O₆S

There total 10 articles about C₃₀H₂₅Cl₃N₂O₆S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-(N-4-methylbenzamide)-3-(chloromethyl)-8-oxo-5-oxo-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid diphenylmethyl ester (91177-27-4) → C30H25Cl3N2O6S (1370637-75-4)

Guidance literature:

Multi-step reaction with 3 steps

1: tert-butylhypochlorite / methanol; dichloromethane / -45 °C

2: pyridine; phosphorus pentachloride / methanol; dichloromethane / -40 °C

3: pyridine; trichlorophosphate / methanol; dichloromethane / -40 - 0 °C

With pyridine; tert-butylhypochlorite; phosphorus pentachloride; trichlorophosphate; In methanol; dichloromethane;

DOI:10.1016/j.cclet.2012.01.014

Reference yield:

[(2,5-dichlorophenyl)thio]acetic acid (6274-27-7) + (6R,7R)-benzhydryl 7-amino-3-(chloromethyl)-7-methoxy-8-oxo-5-oxa-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate → C30H25Cl3N2O6S (1370637-75-4)

Guidance literature:

With pyridine; trichlorophosphate; In methanol; dichloromethane; at -40 - 0 ℃;

DOI:10.1016/j.cclet.2012.01.014

Reference yield:

6β-(4-toluamido)penicillanic acid (17028-66-9) → C30H25Cl3N2O6S (1370637-75-4)

Guidance literature:

Multi-step reaction with 10 steps

1.1: pyridine; methanesulfonyl chloride / -5 - 10 °C

2.1: sodium tungstate; dihydrogen peroxide / 0 °C

3.1: chloro-trimethyl-silane; triethylamine / 10 °C

4.1: triphenylphosphine / ethyl acetate / 78 °C

5.1: chlorine; sodium hydrogencarbonate / water; ethyl acetate / 20 - 25 °C

5.2: 25 °C

6.1: pyridine; chlorine / dichloromethane

7.1: diethylamine / -20 °C

8.1: tert-butylhypochlorite / methanol; dichloromethane / -45 °C

9.1: pyridine; phosphorus pentachloride / methanol; dichloromethane / -40 °C

10.1: pyridine; trichlorophosphate / methanol; dichloromethane / -40 - 0 °C

With pyridine; sodium tungstate; chloro-trimethyl-silane; tert-butylhypochlorite; phosphorus pentachloride; dihydrogen peroxide; chlorine; sodium hydrogencarbonate; methanesulfonyl chloride; diethylamine; triethylamine; triphenylphosphine; trichlorophosphate; In methanol; dichloromethane; water; ethyl acetate;

DOI:10.1016/j.cclet.2012.01.014

upstream raw materials:

6β-(4-toluamido)penicillanic acid

C₂₉H₂₈N₂O₅S

C₂₉H₂₆N₂O₄

diphenylmethyl (2R,6R,7R)-3-methylene-7-[(4-methylbenzoyl)amino]-8-oxo-5-oxa-1-azabicyclo[4.2.0]octane-2-carboxylate

Downstream raw materials:

C₃₅H₃₀Cl₂N₃O₆S⁽¹⁺⁾*I^(1-)

C₃₈H₃₄Cl₂N₃O₆S⁽¹⁺⁾*I^(1-)

C₂₂H₂₀Cl₂N₃O₆S⁽¹⁺⁾*I^(1-)

C₂₅H₂₄Cl₂N₃O₆S⁽¹⁺⁾*I^(1-)