Bromomethanesulfonyl chloride

Base Information

• Chemical Name: Bromomethanesulfonyl chloride
• CAS No.: 10099-08-8
• Molecular Formula: CH₂BrClO₂S
• Molecular Weight: 193.449
• European Community (EC) Number: 818-230-2
• Mol file: 10099-08-8.mol

Synonyms:bromomethanesulfonyl chloride;10099-08-8;BromomethanesulfonylChloride;CH2BrClO2S;SCHEMBL1596313;MFCD11200854;AKOS009269470;AT12635;BS-12664;EN300-43523

Chemical Property of Bromomethanesulfonyl chloride

Chemical Property:

• Boiling Point: 215.1±23.0 °C(Predicted)
• Density: 2.134±0.06 g/cm3(Predicted)
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 191.86474
• Heavy Atom Count: 6
• Complexity: 110

Purity/Quality:

97% ^*data from raw suppliers

BromomethanesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(S(=O)(=O)Cl)Br

Technology Process of Bromomethanesulfonyl chloride

There total 5 articles about Bromomethanesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

bromomethanesulfonic acid,sodium salt (34239-78-6) → bromomethanesulfonyl chloride (10099-08-8)

Guidance literature:

With phosphorus pentachloride; at 70 - 130 ℃; for 1h;

DOI:10.1016/j.bmcl.2008.09.004

Reference yield: 79.0%

methanesulfonyl trimethylsilyl chloride (18143-34-5) → bromomethanesulfonyl bromide (54730-18-6) + bromomethanesulfonyl chloride (10099-08-8)

Guidance literature:

With tetraethylammonium chloride; bromine; cesium fluoride; In acetonitrile; Ambient temperature; addition at 0 deg C;

DOI:10.1016/S0040-4039(00)88704-3

Reference yield:

1,1-dibromomethane (74-95-3) → bromomethanesulfonyl chloride (10099-08-8)

Guidance literature:

With phosphorus pentachloride; tetra(n-butyl)ammonium hydrogensulfate; sodium sulfite; Yield given. Multistep reaction; 1.) reflux, 26 h, 2.) a) 130 deg C, 45 min, b) 70 deg C, 30 min;

DOI:10.1021/jm00395a010

upstream raw materials:

methanesulfonyl chloride

bromomethanesulfonic acid,sodium salt

methanesulfonyl trimethylsilyl chloride

1,1-dibromomethane

Downstream raw materials:

N-cyclohexyl bromomethanesulfonamide

1-bromo-N,N-dimethylmethanesulfonamide

4-((bromomethyl)sulfonyl)morpholine

Bromo-methanesulfonic acid 2-chloro-ethyl ester