Sodium bromomethylsulfonate

Base Information

• Chemical Name: Sodium bromomethylsulfonate
• CAS No.: 34239-78-6
• Molecular Formula: CH3BrO3S
• Molecular Weight: 196.985
• Mol file: 34239-78-6.mol

Synonyms:Sodium bromomethanesulfonate; Sodium bromomethylsulfonate

Chemical Property of Sodium bromomethylsulfonate

Chemical Property:

• Melting Point: 272-278℃
• Refractive Index: 1.558
• PSA: 62.75000
• Density: 2.279 g/cm³
• LogP: 1.30740

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sodium bromomethylsulfonate

There total 1 articles about Sodium bromomethylsulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,1-dibromomethane (74-95-3) → bromomethanesulfonic acid,sodium salt (34239-78-6)

Guidance literature:

With sodium sulfite; In water; for 80h; Heating / reflux;

Reference yield: 93.0%

bromomethanesulfonic acid,sodium salt (34239-78-6) → bromomethanesulfonyl chloride (10099-08-8)

Guidance literature:

With phosphorus pentachloride; at 70 - 130 ℃; for 1h;

DOI:10.1016/j.bmcl.2008.09.004

Reference yield: 79.2%

6-hydroxy-2-phenyl-3(2H)-pyridazinone (1698-54-0) + bromomethanesulfonic acid,sodium salt (34239-78-6) → sodium; (6-oxo-1-phenyl-1,6-dihydro-pyridazin-3-yloxy)-methanesulfonate

Guidance literature:

With sodium hydroxide; Heating;

DOI:10.1023/A:1022182526868

upstream raw materials:

1,1-dibromomethane

Downstream raw materials:

bromomethanesulfonyl chloride

(4-{(R)-2-[(R)-5-(3-Chloro-phenyl)-2-oxo-oxazolidin-3-yl]-propyl}-phenoxy)-methanesulfonic acid

[(4-{(2R)-2-[(1E)-3-hydroxy-4-phenylbut-1-enyl]-5-oxopyrrolidin-1-yl}butyl)thio]methanesulfonic acid

[(2-chlorophenyl)oxy]methanesulfonic acid sodium salt

Refernces

• 1、 Zhang, Zai-Wei,Wang, Shi-Meng,Fang, Wan-Yin,Lekkala, Ravindar,Qin, Hua-Li. "Protocol for Stereoselective Construction of Highly Functionalized Dienyl Sulfonyl Fluoride Warheads". . p. 13721 - 13734. Retrieved 2020/12/15.
• 2、 Bonnet, Muriel,Hong, Cho Rong,Wong, Way Wua,Liew, Lydia P.,Shome, Avik,Wang, Jingli,Gu, Yongchuan,Stevenson, Ralph J.,Qi, Wen,Anderson, Robert F.,Pruijn, Frederik B.,Wilson, William R.,Jamieson, Stephen M. F.,Hicks, Kevin O.,Hay, Michael P.. "Next-Generation Hypoxic Cell Radiosensitizers: Nitroimidazole Alkylsulfonamides". supporting information. p. 1241 - 1254. Retrieved 2018/02/17.