3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

Base Information

Chemical Name:3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate
CAS No.:721952-78-9
Molecular Formula:C₂₉H₃₃F₂N₃O₄
Molecular Weight:525.596
Hs Code.:

Synonyms:3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

Suppliers and Price of 3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

There total 1 articles about 3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 721952-75-6
1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinecarboxylic acid

: 6148-64-7
ethyl potassium malonate

: 721952-78-9
3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

Guidance literature:: ethyl potassium malonate; With magnesium chloride; In tetrahydrofuran; at 65 ℃; for 4h;

1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinecarboxylic acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 12h;

Reference yield: 25.0%

: 721952-78-9
3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate

: 124-42-5
acetamidine hydrochloride

: 721952-79-0
5,5-bis(4-fluorophenyl)-3-{3-[4-(6-hydroxy-2-methyl-4-pyrimidinyl)-1-piperidinyl]propyl}-2-methyl-3,5-dihydro-4H-imidazol-4-one

Guidance literature:: acetamidine hydrochloride; With sodium ethanolate; In ethanol; at 80 ℃; for 2h;

3-(1-{3-[4,4-bis(4-fluorophenyl)-2-methyl-5-oxo-4,5-dihydro-1H-imidazol-1-yl]propyl}-4-piperidinyl)-3-oxopropanoate; In ethanol; for 12h; Heating / reflux;

With hydrogenchloride; In ethanol; water; pH=6;