Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI)

Base Information

Chemical Name:Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI)
CAS No.:302553-78-2
Molecular Formula:C₁₅H₂₀N₂O₃
Molecular Weight:276.335
Hs Code.:
Mol file:302553-78-2.mol

Synonyms:Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI)

Suppliers and Price of Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI)

Chemical Property:

PSA：0.00000
LogP:0.00000

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI)

There total 4 articles about Carbamic acid, [cis-4-(aminocarbonyl)cyclohexyl]-, phenylmethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 34771-04-5
(1r,4r)-4-(((benzyloxy)carbonyl)amino)cyclohexane carboxylic acid

: 302553-78-2
benzyl ((1r,4r)-4-carbamoylcyclohexyl)carbamate

Guidance literature:: With ammonium chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 19h;

Reference yield:

: 1776-53-0,3685-23-2,3685-25-4,57043-03-5,66762-20-7
trans-4-aminocyclohexanecarboxylic acid

: 302553-78-2
benzyl ((1r,4r)-4-carbamoylcyclohexyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 3 h / 0 - 35 °C

2.1: isobutyl chloroformate; 4-methylmorpholine N-oxide / tetrahydrofuran / 1.5 h / -78 °C

2.2: 1.5 h / -78 - 35 °C

With 4-methylmorpholine N-oxide; sodium hydroxide; isobutyl chloroformate; In tetrahydrofuran; water;

Reference yield:

: 1885-14-9
phenyl chloroformate

: 302553-78-2
benzyl ((1r,4r)-4-carbamoylcyclohexyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 3 h / 0 - 35 °C

2.1: isobutyl chloroformate; 4-methylmorpholine N-oxide / tetrahydrofuran / 1.5 h / -78 °C

2.2: 1.5 h / -78 - 35 °C

With 4-methylmorpholine N-oxide; sodium hydroxide; isobutyl chloroformate; In tetrahydrofuran; water;