2-Isopropylthiazole-4-carboxamide

Base Information

Chemical Name:2-Isopropylthiazole-4-carboxamide
CAS No.:390386-23-9
Molecular Formula:C₇H₁₀N₂OS
Molecular Weight:170.235
Hs Code.:2934100090
DSSTox Substance ID:DTXSID90456113
Nikkaji Number:J1.665.021H
Wikidata:Q82278332
Mol file:390386-23-9.mol

Synonyms:2-Isopropylthiazole-4-carboxamide;390386-23-9;2-(propan-2-yl)-1,3-thiazole-4-carboxamide;SCHEMBL5520265;DTXSID90456113;ZHTIQAPVCFSHDH-UHFFFAOYSA-N;AKOS016002798;2-Isopropyl-thiazole-4-carboxylic amide;4-thiazolecarboxamide,2-(1-methylethyl)-;2-isopropyl-thiazole-4-carboxylic acid amide

Suppliers and Price of 2-Isopropylthiazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Isopropylthiazole-4-carboxamide 95+%
5g
$ 708.00

Chemenu
2-Isopropylthiazole-4-carboxamide 95%
5g
$ 669.00

American Custom Chemicals Corporation
2-ISOPROPYLTHIAZOLE-4-CARBOXAMIDE 95.00%
5MG
$ 504.75

Total 7 raw suppliers

Chemical Property of 2-Isopropylthiazole-4-carboxamide

Chemical Property:

PSA：85.21000
LogP:2.24960
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:170.05138412
Heavy Atom Count:11
Complexity:161

Purity/Quality:

97% ^*data from raw suppliers

2-Isopropylthiazole-4-carboxamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=NC(=CS1)C(=O)N

Technology Process of 2-Isopropylthiazole-4-carboxamide

There total 5 articles about 2-Isopropylthiazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 133047-44-6
2-isopropyl-thiazole-4-carboxylic acid ethyl ester

: 390386-23-9
2-isopropylthiazole-4-carboxylic acid amide

Guidance literature:: With ammonia; In methanol; at 20 ℃; for 15h;
DOI:10.1021/jo0106905

Reference yield:

: 336193-96-5
methyl 2-isopropylthiazole-4-carboxylate

: 390386-23-9
2-isopropylthiazole-4-carboxylic acid amide

Guidance literature:: With ammonia; In methanol;
DOI:10.1016/S0040-4039(01)02207-9

Reference yield:

: 76275-87-1
methyl 2-acetylthiazole-4-carboxylate

: 390386-23-9
2-isopropylthiazole-4-carboxylic acid amide

Guidance literature:: Multi-step reaction with 3 steps

1.1: tert-BuOK / toluene / 1 h / Heating

1.2: 93 percent / toluene / 1 h / Heating

2.1: H₂ / 5 percent Pd/C / methanol

3.1: NH₃ / methanol / 72 h / 20 °C

With potassium tert-butylate; ammonia; hydrogen; palladium on activated charcoal; In methanol; toluene; 1.2: Wittig olefination;
DOI:10.1016/S0040-4020(03)00300-4