Technology Process of Tert-butyl 4-(4-oxobutan-2-yl)benzoate
There total 4 articles about Tert-butyl 4-(4-oxobutan-2-yl)benzoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -60 ℃;
for 0.25h;
DOI:10.1248/cpb.49.1280
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 79 percent / toluene / 2 h / Heating
2: 39 percent / Me3SiCl / diethyl ether / 3 h / -78 - 20 °C
3: 96 percent / LiBH4 / diethyl ether / 13 h / 20 °C
4: 93 percent / (COCl)2; DMSO / CH2Cl2 / 0.25 h / -60 °C
With
lithium borohydride; chloro-trimethyl-silane; oxalyl dichloride; dimethyl sulfoxide;
In
diethyl ether; dichloromethane; toluene;
4: Swern oxidation;
DOI:10.1248/cpb.49.1280
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 39 percent / Me3SiCl / diethyl ether / 3 h / -78 - 20 °C
2: 96 percent / LiBH4 / diethyl ether / 13 h / 20 °C
3: 93 percent / (COCl)2; DMSO / CH2Cl2 / 0.25 h / -60 °C
With
lithium borohydride; chloro-trimethyl-silane; oxalyl dichloride; dimethyl sulfoxide;
In
diethyl ether; dichloromethane;
3: Swern oxidation;
DOI:10.1248/cpb.49.1280
