65874-27-3

Basic information

• Product Name: 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
• Synonyms: 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER;4-ForMyl-benzoic acid Mono tert-butyl ester(70%);tert-butyl 4-forMylbenzoate
• CAS NO: 65874-27-3
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Mol File: 65874-27-3.mol
• Article Data: 23

Chemical Properties

• Melting Point: 52.0 to 56.0 °C
• Boiling Point: 310.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.093±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER(65874-27-3)
• EPA Substance Registry System: 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER(65874-27-3)

Safety Data

• Hazardous Substances Data: 65874-27-3(Hazardous Substances Data)

Usage

General Description

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER is a chemical compound that is commonly used in the field of organic chemistry. It is a ester derivative of 4-formyl-benzoic acid, which is often used as a building block for the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER is a colorless solid that is soluble in organic solvents, and it is commonly used as a reagent in organic reactions. It is important to handle this compound with care as it can be hazardous if it comes into contact with the skin or if it is inhaled.

Upstream product

• 13756-42-8 tert-butyl 4-methylbenzoate 
• 16173-52-7 4-formylbenzoyl chloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 619-66-9 4-Carboxybenzaldehyde 
• 59247-47-1 tert-butyl-4-bromobenzoate 
• 68-12-2 N,N-dimethyl-formamide 
• 36805-97-7 N,N-dimethylformamide di-tert-butyl acetal 
• 75-65-0 tert-butyl alcohol 
• 71432-55-8 2-tert-butyl-1,3-diisopropylisourea 
• 98946-18-0 tert-Butyl 2,2,2-trichloroacetimidate 

Downstream Products

• 149324-85-6 4-(t-butoxycarbonyl)phenylpropanol 
• 1072800-44-2 7-butyl-7-(α-hydroxy-4-(tert-butoxycarbonyl)benzyl)-8,11-dithiapentadec-5-yne 
• 1435936-43-8 t-butyl 4-[[(4-methoxyphenyl)imino]methyl]benzoate 
• 1435936-22-3 C₂₀H₂₃NO₅ 
• 732308-81-5 tert-butyl 4-(2-methoxyethenyl)benzoate 
• 1004759-91-4 tert-butyl 4-((dimethylamino)methyl)benzoate 
• 18364-71-1 4-((dimethylamino)methyl)benzoic acid 

Relevant articles and documents

Metal- And additive-free C-H oxygenation of alkylarenes by visible-light photoredox catalysis

A metal- and additive-free methodology for the highly selective, photocatalyzed C-H oxygenation of alkylarenes under air to the corresponding carbonyls is presented. The process is catalyzed by an imide-acridinium that forms an extremely strong photooxidant upon visible light irradiation, which is able to activate inert alkylarenes such as toluene. Hence, this is an easy to perform, sustainable and environmentally friendly oxidation that provides valuable carbonyls from abundant, readily available compounds.

Hapten design and monoclonal antibody to fluoroacetamide, a small and highly toxic chemical

Fluoroacetamide (FAM) is a small (77 Da) and highly toxic chemical, formerly used as a rodenticide and potentially as a poison by terrorists. Poisoning with FAM has occurred in humans, but few reliably rapid detection methods and antidotes have been reported. Therefore, producing a specific antibody to FAM is not only critical for the development of a fast diagnostic but also a potential treatment. However, achieving this goal is a great challenge, mainly due to the very low molecular weight of FAM. Here, we design two groups of FAM haptens for the first time, maximally exposing the fluorine or amino groups, with the aid of linear aliphatic or phenyl-contained spacer arms. Interestingly, whereas the hapten with fluorine at the far end of the hapten did not induce an antibody response to FAM, the hapten with an amino group at the far end and phenyl-contained spacer arm triggered a significantly specific antibody response. Finally, a monoclonal antibody (mAb) named 5D11 was successfully obtained with an IC50 value of 97 μg mL?1 and negligible cross-reactivities to the other nine functional and structural analogs.

DIAZANAPHTHALEN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF

Diazanaphthalene compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a diazanaphthalene compound or analogs thereof, in the treatment of disorders characterized by the activa