(4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

Base Information

Chemical Name:(4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline
CAS No.:340131-67-1
Molecular Formula:C₂₅H₂₅NO₂
Molecular Weight:371.479
Hs Code.:

Synonyms:(4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

Suppliers and Price of (4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

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Technology Process of (4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

There total 1 articles about (4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 23190-16-1
(1R,2S)-2-Amino-1,2-diphenylethanol

: 340131-70-6
2-hydroxy-3-tert-butyl benzonitrile

: 340131-67-1
(4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

Guidance literature:: With zinc(II) chloride; In chlorobenzene; for 20h; Heating;
DOI:10.1016/S0022-328X(00)00687-2

Reference yield: 75.0%

: 6046-93-1
copper(II) acetate monohydrate

: 340131-67-1
(4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-hydroxy-3'-tert-butylphenyl)-oxazoline

: bis[(4S,5R)-4,5-dihydro-4,5-diphenyl-2-(2'-oxido-3'-tert-butylphenyl-χO)oxazole-χN]copper(II)

Guidance literature:: In ethanol; addn. of a soln. of copper acetate in abs. ethanol to a soln. of ligand in abs. ethanol, stirring at room temp. for 16 h; filtration, washing with abs. ethanol three times; elem. anal.;
DOI:10.1016/S0022-328X(00)00687-2