2,5-Pyrrolidinedione,1-[(1-oxo-3-butenyl)oxy]-(9CI)

Base Information

• Chemical Name: 2,5-Pyrrolidinedione,1-[(1-oxo-3-butenyl)oxy]-(9CI)
• CAS No.: 388091-45-0
• Molecular Formula: C₈H₉NO₄
• Molecular Weight: 183.164
• Mol file: 388091-45-0.mol

Synonyms:2,5-Pyrrolidinedione,1-[(1-oxo-3-butenyl)oxy]- (9CI); Succinimidyl 3-butenoate

Chemical Property of 2,5-Pyrrolidinedione,1-[(1-oxo-3-butenyl)oxy]-(9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dioxopyrrolidin-1-yl but-3-enoate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,5-Pyrrolidinedione,1-[(1-oxo-3-butenyl)oxy]-(9CI)

There total 2 articles about 2,5-Pyrrolidinedione,1-[(1-oxo-3-butenyl)oxy]-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.7%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + but-3-enoic acid (625-38-7) → 2,5-dioxopyrrolidin-1-yl but-3-enoate (388091-45-0)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃; for 8h;

DOI:10.1039/c4cc06435f

Reference yield:

N-trifluoroacetoxy succinimide (5672-89-9) + but-3-enoic acid (625-38-7) → 2,5-dioxopyrrolidin-1-yl but-3-enoate (388091-45-0)

Guidance literature:

With pyridine; In tetrahydrofuran; at 0 - 20 ℃; for 24h;

DOI:10.1021/ol0702066

Reference yield: 79.0%

2,5-dioxopyrrolidin-1-yl but-3-enoate (388091-45-0) + tryptamine (61-54-1) + carbon monoxide (201230-82-2) → 1,2,3,4,6,7,12,12b-octahydroindolo<2,3-a>quinolizine-4-one (4942-85-2)

Guidance literature:

With dicarbonylacetylacetonato rhodium(I); boron trifluoride diethyl etherate; hydrogen; 6,6′-[(3,3′-di-tert-butyl-5,5′-dimethoxy-1,1′-biphenyl-2,2′-diyl)bis(oxy)]bis(di-benzo[d,f][1,3,2]dioxaphosphepin); In tetrahydrofuran; at 70 ℃; for 12h; under 3750.38 Torr; Autoclave;

DOI:10.1021/ol902279m

upstream raw materials:

N-trifluoroacetoxy succinimide

but-3-enoic acid

1-hydroxy-pyrrolidine-2,5-dione

Downstream raw materials:

1,2,3,4,6,7,12,12b-octahydroindolo<2,3-a>quinolizine-4-one